| 腺苷脱氨酶检测对结核性脑膜炎诊断的临床价值 |
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| 引用本文： | 吴泉,邹伟华,王笑颜,顾金华,谈鹰,钱福初.腺苷脱氨酶检测对结核性脑膜炎诊断的临床价值[J].疾病监测,2010,25(2):157-159. |
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| 作者姓名： | 吴泉 邹伟华 王笑颜 顾金华 谈鹰 钱福初 |
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| 作者单位： | 1.浙江省湖州师范学院医学院附属中心医院检验科,浙江 湖州 313000 |
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| 摘 要： | 目的评价脑脊液中腺苷脱氨酶(ADA)检测对结核性脑膜炎诊断的应用价值。方法采用酶显色法检测102例4组病例(结核性脑膜炎组30例,化脓性脑膜炎组34例,病毒性脑膜炎组15例,头痛症状组23例)脑脊液中ADA的活性水平。结果30例结核性脑膜炎组脑脊液中ADA活性明显增高,ADA6.0U/L26例,与化脓性脑膜炎组比较差异有统计学意义(P0.01),敏感性为86.7%(26/30),特异性为91.7%(66/72)。化脓性脑膜炎组和病毒性脑膜炎组与头痛症状组(对照组)比较差异也具有统计学意义(P0.05)。结论检测脑脊液中ADA的活性对于结核性脑膜炎诊断和鉴别诊断有重要的临床价值。
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| 关 键 词： | 腺苷脱氨酶 结核性脑膜炎 脑脊液 |
| 收稿时间： | 2009-09-16 |
Diagnostic value of adenosine deaminase activity in tuberculous Meningitis |
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| WU Quan
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ZOU Wei-hua
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WANG Xiao-yan
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GU Jin-hun
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TAN Ying
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QIAN Fu-chu.Diagnostic value of adenosine deaminase activity in tuberculous Meningitis[J].Disease Surveillance,2010,25(2):157-159. |
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| Authors: | WU Quan ZOU Wei-hua WANG Xiao-yan GU Jin-hun TAN Ying QIAN Fu-chu |
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| Institution: | 1.Zhejiang Central Hospital Clinical Laboratory Affiliated to Medical College of Huzhou Normal College, Huzhou 313000, Zhejiang, China |
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| Abstract: | Objective To assess the diagnostic value of adenosine deaminase(ADA) activity in the cerebrospinal fluid of tuberculous meningitis patients.Methods The ADA enzyme was measured spectrophotometrically to determine the ADA activity in the cerebrospinal fluid of 102 patients,who were divided into four groups(30 with tuberculous meningitis,34 with bacterial meningitis,15 with viral meningitis,and 23 with mere headaches).Results The ADA activity was significantly elevated in the cerebrospinal fluid of 30 patients... |
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| Keywords: | adenosine deaminase tuberculous meningitis cerebrospinal fluid |
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