| 血管内皮生长因子与脑梗死 |
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| 引用本文： | 邓可,吴晓球,肖志杰.血管内皮生长因子与脑梗死[J].国际脑血管病杂志,2010,18(7). |
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| 作者姓名： | 邓可 吴晓球 肖志杰 |
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| 作者单位： | 1. 湖南师范大学附属岳阳医院,岳阳市二人民医院神经内科,岳阳,414000
2. 中南大学湘雅二医院神经内科,长沙,410011 |
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| 摘 要： | 血管内皮生长因子(vascular endothelial growth factor,VEGF)是血管内皮细胞的一种特异性促分裂原,是最重要的促血管新生因子.VEGF在脑梗死后高度表达,在血管新生和神经保护中起着重要作用;同时,其过度表达也会使血管通透性增加,进而可能加重脑水肿.文章对VEGF及其受体与脑梗死的研究进展进行了综述.
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| 关 键 词： | 血管内皮生长因子 受体 血管内皮生长因子 脑梗死 |
Vascular endothelial growth factor and cerebral infarction |
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| DENG Ke,WU Xiao-qiu,XIAO Zhi-jie.Vascular endothelial growth factor and cerebral infarction[J].International Journal of Cerebrovascular Diseases,2010,18(7). |
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| Authors: | DENG Ke WU Xiao-qiu XIAO Zhi-jie |
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| Abstract: | Vascular endothelial growth factor is a vascular endothelial cell-specific mitogen.It is the most important angiogenic factor.VEGF expresses highly after cerebral infarction.It plays importmt roles in angiogenesis and neuroprotection.At the same time,its overexpression will also increase vascular permeability;thereby it may aggravate brain edema.This article reviews the advances in research on VEGF and its receptors and cerebral infarction. |
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| Keywords: | Vascular endothelial growth factors Receptors vascular endothelial growth factor Brain infarction |
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