| 贝那普利与左旋氨氯地平联用对原发性高血压合并2型糖尿病微量蛋白尿的影响 |
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| 引用本文： | 刘明江,李杰,陶剑虹,唐英容.贝那普利与左旋氨氯地平联用对原发性高血压合并2型糖尿病微量蛋白尿的影响[J].四川医学,2010,31(3):297-299. |
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| 作者姓名： | 刘明江 李杰 陶剑虹 唐英容 |
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| 作者单位： | 四川省人民医院心内科,四川,成都,610072 |
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| 摘 要： | 目的探讨联合应用贝那普利（洛丁新）和左旋氨氯地平（施慧达）对原发性高血压合并2型糖尿病微量蛋白尿的影响。方法200例原发性高血压合并2型糖尿病微量蛋白尿阳性住院及门诊患者。在严格控制血糖的基础上,随机分成3组,分别用贝那普利、左旋氨氯地平、贝那普利＋左旋氨氯地平联合治疗6个月,观察治疗前后3组患者24h动态血压、糖化血红蛋白、24h尿微量蛋白的变化。结果3组患者血压均较治疗前降低,联合治疗组较单药治疗组下降明显,且有统计学意义（P〈0.05）。治疗后联合治疗组微量蛋白尿较单用治疗组下降明显,有统计学意义（P〈0.05）。结论贝那普利和左旋氨氯地平联合应用,既能很好地控制血压,又能明显地降低尿蛋白,保护肾功能。在临床上,对于原发性高血压合并2型糖尿病微量蛋白尿的患者,值得早期推广使用。
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| 关 键 词： | 贝那普利 左旋氨氯地平 原发性高血压合并2型糖尿病 微量蛋白尿 |
Combinative treatment effects of benazepril and levamlodipine against microdose proteinuria in patients with essential hypertension and type 2 diabetes mellitus |
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| Institution: | LIU Ming-jiang,LI Jie,TAO Jian-Hong,et al(The People′s Hospital of Sichuan,Chengdu,Sichuan 610072,China ) |
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| Abstract: | Objective To investigate the combinative treatment effects of benazepril and levamlodipine against microdose proteinuria in patients with essential hypertension and 2 diabetes mellitus.Methods 200 patients with both essential hypertension and 2 diabetes mellitus were studied.The blood glucose of the patients were under well controled.The patients were divided randomly into 3 groups.Group one was treated by Benazepril only.While group two by levamlodipine only.Group three by both.After 6 months,investigate t... |
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| Keywords: | benazepril levamlodipine hypertension 2 diabetes mellitus microdose proteinuria |
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