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Inappropriate ICD shocks do not induce pro-arrhythmic electrocardiographic changes in men
Authors:Bert Vandenberk  Katerina Hnatkova  Griet Goovaerts  Christophe Garweg  Joris Ector  Sabine Van Huffel
Affiliation:1. Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium;2. Department of Clinical Cardiology, University Hospitals Leuven, Leuven, Belgium;3. National Heart and Lung Institute, Imperial College, London, England;4. Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, University of Leuven, Leuven, Belgium;5. iMinds, Medical IT, Leuven, Belgium
Abstract:Objectives: Longer-term electrocardiographic effects of multiple inappropriate ICD shocks were investigated to study their hypothesized pro-arrhythmic potential.

Design: Thirteen male patients with ischemic cardiomyopathy who received ≥2 inappropriate shocks within 24?h and for whom 12-lead ECGs were available both before and within 72h after the inappropriate shocks were analyzed. Exclusion criteria included continuous ventricular pacing, underlying AF, events within 6 weeks after lead implantation and concomitant acute medical problems.

Results: A total of 149 inappropriate shocks (mean 11?±?19) were received. There were no significant differences in any of the measured intervals or morphological indices, nor was there a correlation between the “before-after” differences and the number of shocks received. Non-significant changes showed Percentage of Loop Area increase and relative T-wave Residuum decrease while the opposite changes have previously been associated with arrhythmic risk.

Conclusions: No potentially pro-arrhythmic electrocardiographic changes were found 19?h after multiple inappropriate shocks.
Keywords:Electrocardiography  implantable cardioverter-defibrillator  inappropriate shocks
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