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倍他乐克治疗慢性重度充血性心力衰竭的疗效观察
引用本文:张红,岳瑞华,沈钧乐,李婷婷,徐幸,史若飞.倍他乐克治疗慢性重度充血性心力衰竭的疗效观察[J].重庆医学,2008,37(9):969-970.
作者姓名:张红  岳瑞华  沈钧乐  李婷婷  徐幸  史若飞
作者单位:重庆市急救医疗中心,400014;重庆市急救医疗中心心脏彩超室,400014
摘    要:目的观察倍他乐克治疗慢性重度充血性心力衰竭患者的疗效。方法选择心功能Ⅲ~Ⅳ级慢性充血性心力衰竭患者60例,随机分成两组,所有患者均接受心力衰竭的常规治疗2周,治疗组在常规抗心衰治疗基础上加用倍他乐克,根据患者耐受程度8周内逐渐加量至最大耐受量100mg/次,2次/d,疗程均为9个月。结果治疗组心功能改善总有效率90.0%,对照组76.7%,两组比较差异有统计学意义(P<0.05);治疗组治疗后较治疗前LVEF增加,LVDd减少,与对照组比较,差异有统计学意义(P<0.01)。结论在常规抗心衰治疗的基础上加用倍他乐克治疗慢性重度充血性心力衰竭取得较好疗效。

关 键 词:倍他乐克  慢性重度充血性心力衰竭  疗效
文章编号:1671-8348(2008)09-0969-02
修稿时间:2007年10月2日

Observation of curative effect of chronic advanced congestive heart failure treated by metoprolol
ZHANG Hong,YUE Rui-hua,SHEN Jun-le,et al..Observation of curative effect of chronic advanced congestive heart failure treated by metoprolol[J].Chongqing Medical Journal,2008,37(9):969-970.
Authors:ZHANG Hong  YUE Rui-hua  SHEN Jun-le  
Abstract:Objective To observe the curative effect of metoprolol in the treatment of chronic advanced congestive heart failure.Methods Sixty patients with chronic advanced congestive heart failure in heart function three to four grade were collected.All the patients classified randomly into two groups(treatment group and control group).All cases were treated by anti-heart failure in routine methods for two weeks.Metoprolol was administered in treatment group gradually up to the dosage of 100mg bid in eight weeks,for nine months.Results The curative effect of treatment group was significantly higher than those of control group.Improved in heart function at treatment group,the rate of efficiency were 90.0%,76.7% in treatand control group,P<0.05;LVEF increased,LVDd decreased at treatment group(P<0.01).Conclusion The curative effect is better for patients with chronic advanced congestive heart failure by metoprolol with routine methods.
Keywords:metoprolol  chronic advanced congestive heart failure  curative effection
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