嗜麦芽窄食单胞菌的耐药性监测

目的 了解临床分离的嗜麦芽窄食单胞菌的耐药情况。方法 采用MicroScan WalkAWay-40全自动微生物分析仪对2000年1月1日～2003年12月31日安徽医科大学第一附属医院临床分离的74株嗜麦芽窄食单胞菌的耐药性进行测定。结果 嗜麦芽窄食单胞菌对亚胺培南、氨曲南、头孢曲松、庆大霉素、妥布霉素、头孢噻肟、阿米卡星、哌拉西林、头孢他啶、环丙沙星的耐药率均在50％以上，复方新诺明的耐药率最低，为5．3％～19．2％；痰标本来源菌株所占比例最高，为67．6％；分离患者中60岁以上的占70．3％；干部病房、重症监护病房（intensive care unit，ICU）和血液内科占43．2％。结论 嗜麦芽窄食单胞菌为多重耐药菌株，临床上应加强耐药性监测和合理用药。

Surveillance on the bacterial resistance in Stenotrophomonas maltophilia

ObjectiveTo investigate the bacterial resistance of Stenotrophomonas maltophilia isolates. MethodsThe resistance of 74 isolates from our hospital from 2000 to 2003 was tested by MicroScan WalkAWay-40. ResultsThe rate of resistance to imipenem, aztreonam, ceftriaxone, gentamicin, tobramycin, cefotaxime, amikacin, piperacillin, ceftazidime, ciprofloxacin was more than 50% respectively, but only SMZ-TMP Co resistance rate being 5.3%19.2%. Isolates were mainly cultured from sputum specimens (67.6%). 70.3% of the sample were isolated from old patients, while 43.2% from ICU, cadre wards and blood wards. ConclusionsStenotrophomonas maltophilia are multi-drug resistant. It is important to perform surveillance of their resistance and use antimicrobial agents reasonably.