A prospective, double-blind, randomized trial of caudal block using ropivacaine 0.2% with or without fentanyl 1 microg kg-1 in children |
| |
Authors: | Kawaraguchi Y Otomo T Ota C Uchida N Taniguchi A Inoue S |
| |
Affiliation: | 1 Department of Anaesthesia and Critical Care, Miyagi Children's Hospital Sendai, Japan 2 Department of Anaesthesiology, Nara Medical University Kashihara, Japan |
| |
Abstract: | Background. It has been reported that ropivacaine produces vasoconstrictionin contrast to vasodilation produced by bupivacaine. It is possiblethat additives to ropivacaine can provide further analgesicadvantages compared with bupivacaine. We thus evaluated whetherthe addition of fentanyl to ropivacaine prolonged the durationof analgesia after a single shot caudal block. Methods. A total of 36 children undergoing surgical proceduresbelow the umbilicus were randomly allocated to one of two groups:Group F received ropivacaine 0.2%, 1 ml kg1 with fentanyl1 µg kg1 and Group S received ropivacaine 0.2%,1 ml kg1 with saline. The analgesic effect of the caudalblock was evaluated using the Children's Hospital of EasternOntario Pain Scale (CHEOPS) and sedation was assessed usingthe Steward score at 30 min after extubation and at 1, 2, 4,6, 12 and 24 h. The first analgesic requirement time and side-effectsin a 24 h period were also recorded. Results. There were no differences in characteristics betweenthe groups. The end-tidal concentration of sevoflurane at extubationin Group F was significantly lower than in Group S. However,there was no significant difference in time from discontinuationof the volatile anaesthetics to tracheal extubation. No statisticaldifferences were found in the CHEOPS and Steward score, andthe time to first analgesia. The incidence of postoperativevomiting was not significantly different. Conclusion. We found that the addition of fentanyl 1 µgkg1 to ropivacaine 0.2% for caudal analgesia providesno further analgesic advantages over ropivacaine 0.2% alone. |
| |
Keywords: | analgesia, postoperative analgesics opioid, fentanyl anaesthesia, paediatric anaesthetic techniques, regional, caudal anaesthetics local, ropivacaine |
本文献已被 PubMed Oxford 等数据库收录! |
|