| LAMS抑制肝癌细胞增殖和促凝活性的实验研究 |
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| 引用本文： | 董浦江,姚榛祥.LAMS抑制肝癌细胞增殖和促凝活性的实验研究[J].重庆医科大学学报,2001,26(4):391-392,396. |
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| 作者姓名： | 董浦江 姚榛祥 |
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| 作者单位： | 重庆医科大学临床学院器官移植研究室, |
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| 摘 要： | 目的：观察LAMS抑制肝癌细胞增殖和促凝活性的效果。方法：比较LAMS处理的肝癌细胞生长曲线、AgNoRs含量变化；用一步法APTT测定LAMS拮抗肝癌细胞分泌物的促凝血作用。结果：LAMS处理后的肝癌细胞增殖受抑制、AgNoRs数量减少，LAMS能拮抗肝癌细胞分泌物对APTT的影响。结论：LAMS可有效地抑制肝癌细胞增殖和促凝活性。
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| 关 键 词： | 昆布多糖硫酸酯 肝肿瘤 细胞增殖 促凝活性 LAMS |
| 文章编号： | 0253-3626(2001)04-0391-02 |
Experimental study of LAMS restrain multiplication and procoagulant activity of hepatic cancer cells |
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| DONG Pu-jiang,et al.Experimental study of LAMS restrain multiplication and procoagulant activity of hepatic cancer cells[J].Journal of Chongqing Medical University,2001,26(4):391-392,396. |
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| Authors: | DONG Pu-jiang |
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| Abstract: | Objective: To study the effects of LAMS for restraining multiplication and procoagulant activity of liver cancer cells. Methods: By comparing the growth curves and AgNoRs contents of liver cancer cells treated with or without LAMS.Procoagulant activity of hepatic cancer cells was measured by one step APTT method.Results: After treatment with LAMS,the proliferation of liver cancer cells were inhibited and AgNoRs contents were decreased .LAMS could antagonize the effects of secretion of liver cancer cells on APTT. Conclusion: LAMS can effectively restrain the proliferation and procoagulant activity of hepatic cancer cells. |
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| Keywords: | Laminarin sulphate Hepatic cancer Proliferation Procoagulant |
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