| 骨髓增生异常综合征和急性白血病患者血清可溶性Fas受体检测及意义 |
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| 引用本文： | 马晓星,杨道理,徐军,王鲁群,孔凡盛,刘希民,迟翠芳.骨髓增生异常综合征和急性白血病患者血清可溶性Fas受体检测及意义[J].中国肿瘤生物治疗杂志,1998,5(4):253-255. |
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| 作者姓名： | 马晓星 杨道理 徐军 王鲁群 孔凡盛 刘希民 迟翠芳 |
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| 作者单位： | 济南军区总医院免疫科 济南250031(马晓星，杨道理，徐军)，济南军区总医院血液科 济南250031(王鲁群，孔凡盛，刘希民，迟翠芳) |
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| 摘 要： | 采用ELIS法检测了18例骨髓增生异常综合证(MDS)和42例急性白血病(AL)患者血清sFas受体水平.结果发现,与正常对照组比较,MDS-RA患者血清sFas受体水平显著降低(2.89±1.72ng/ml vs 6.29±1.07ng/ml,P<0.01),而MDS-RAEB/RAEB-t(9.75±2.28ng/ml/19.98±5.24ng/ml)、难治性AL(10.86±3.05ng/ml)和慢性粒细胞白血病急粒变(9.44±4.14ng/ml)均显著升高(P<0.01).提示血清SFas受体与MDS分型、转化和AL的化疗疗效或耐药性密切相关.
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| 关 键 词： | 骨髓增生异常综合征 急性白血病 可溶性Fas受体 凋亡 |
| 收稿时间： | 1998/8/17 0:00:00 |
| 修稿时间： | 9/4/1998 12:00:00 AM |
Detection of the Soluble Fas Receptor Level in Sera from Patients with Myelodysplastic Syndrome and Acute Leukemia and Its Significance |
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| Ma Xiaoxing,Yang Daoli,Xu Jun,Wang Luqun,Sun Fansheng,Liu Ximin and Chi Cuifang.Detection of the Soluble Fas Receptor Level in Sera from Patients with Myelodysplastic Syndrome and Acute Leukemia and Its Significance[J].Chinese Journal of Cancer Biotherapy,1998,5(4):253-255. |
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| Authors: | Ma Xiaoxing Yang Daoli Xu Jun Wang Luqun Sun Fansheng Liu Ximin and Chi Cuifang |
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| Institution: | Department of Immunology, Jinan General Hospital of PIA, Jinan 250031;Department of Immunology, Jinan General Hospital of PIA, Jinan 250031;Department of Immunology, Jinan General Hospital of PIA, Jinan 250031;Department of Immunology, Jinan General Hospital of PIA, Jinan 250031;Department of Immunology, Jinan General Hospital of PIA, Jinan 250031;Department of Immunology, Jinan General Hospital of PIA, Jinan 250031;Department of Immunology, Jinan General Hospital of PIA, Jinan 250031 |
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| Abstract: | |
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| Keywords: | myelodysplastic syndrome acute leukemia soluble Fas receptor apoptosis |
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