胰岛素泵对2型糖尿病患者围手术期血糖控制的临床研究

目的研究使用胰岛素泵对2型糖尿病患者围手术期血糖控制的有效性和安全性。方法选取122例在该院外科进行手术治疗且入院时空腹血糖大于10mmol/L的非初诊2型糖尿病患者,随机分为胰岛素泵持续皮下胰岛素输注组（CSII组）和每日多次皮下注射预混胰岛素组（MSII组）,比较血糖控制达标时两组患者的血糖达标时间、总住院时间、胰岛素平均每日用量等指标。结果当两组血糖达标时CSII组的血糖达标时间、总住院时间、胰岛素平均每日用量和低血糖发生率均显著低于MSII组（P〈0.05）。结论胰岛素泵持续皮下输注与每日多次皮下注射预混胰岛素相比,更接近生理胰岛素的分泌,能更快、更有效安全地控制围手术期血糖。

Clinical Study of Blood Glucose Control Treated with Insulin Pump During Perioperative Period in Type 2 Diabetes Patients

Objective To assay the effectiveness and safety of blood glucose control treated with insulin pump during perioperative period in type 2 diabetes （T2DM） patients.Method One hundred and twenty-two T2DM patients who were not newly diagnosed and FBG10 mmol/L were recruited when they received operation in our hospital,and they were divided into two groups at random,group CSII and group MSII.Time of reaching target of glucose,the insulin dosage and total hospital stay were observed when their blood glucose level reaching standard.Results The time of reaching target of glucose,the insulin dosage,total hospital stay and incidence of hypoglycemia in CSII group were all significantly lower than those in group MSII（P0.05）.Conclusion CSII can make blood glucose level under control more faster,effectively and safely than MSII.