Benign type of central pontinemyelinolysis in alcoholism |
| |
| Authors: | Hitoshi Mochizuki Toshihiro Masaki Tomohiro Miyakawa Jun Nakane Akira Yokoyama Yuji Nakamura Keiji Okuyama Keiko Kamakura Kazuo Motoyoshi Sachio Matsushita Susumu Higuchi |
| |
| Affiliation: | (1) Depts. of Neurology, National Institute on Alcoholism, Kurihama National Hospital, 5-3-1 Nobi Yokosuka, Kanagawa, 239-0841, Japan;(2) Third Dept. of Internal Medicine, National Defense Medical College Tokorozawa, Saitama, Japan;(3) Division of Clinical Research, National Institute on Alcoholism, Kurihama National Hospital Yokosuka, Kanagawa, Japan |
| |
| Abstract: | Nine alcoholic patients with central pontine myelinolysis(CPM),who showed a favorable prognosis, are reported. Themajority of them had taken part in binge drinking and had asubsequent consciousness disturbance for 18.1±10.9 (mean±SD)days. None of the patients had had acute correction ofhyponatremia. Truncal ataxia and gait instability were presentin most of the patients after recovery from the disturbance ofconsciousness. Most of them eventually gained independence, andmagnetic resonance imaging showed that their pontine lesionstended to shrink. Electrophysiological studies detectedprolonged latency between the I and III waves in auditorybrainstem responses and between N11 and P13/14 onsets in thesomatosensory evoked potentials. These clinical, radiologicaland electrophysiological findings should be of use in diagnosingCPM. |
| |
| Keywords: | central pontine myelinolysis alcoholism MRI somatosensory evoked potential auditory brainstem response |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
