| 侧脑室或外周静脉注入5-羟色胺对家兔体动脉血压和肺动脉压的影响 |
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| 引用本文： | 武变瑛,李超英,凌赤凌,黄善生,申文增.侧脑室或外周静脉注入5-羟色胺对家兔体动脉血压和肺动脉压的影响[J].中国病理生理杂志,1992(6). |
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| 作者姓名： | 武变瑛 李超英 凌赤凌 黄善生 申文增 |
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| 作者单位： | 河北职工医学院病理生理教研室
(武变瑛)，河北中医学院病理生理教研室
(李超英)，河北医学院病理生理教研室
(凌赤凌，黄善生)，河北职工医学院病理生理教研室(申文增) |
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| 摘 要： | 本文观察麻醉情况下,侧脑室及耳静脉注入5羟色胺(5-HT),家兔颈动脉血压及肺动脉压的变化。结果发现,耳静脉注入5-HT(100 μg/20 μl)后,肺动脉压上升,颈动脉血压下降,侧脑室注入5-HT后,肺动脉压和颈动脉血压的反应与耳静脉注入柑反。侧脑室注入5-HT引起的肺动脉压及颈动脉血压的变化有阿片样肽类物质的参与;肺动脉压反应还与迷走神经传导及乙酰胆硷的作用有关。
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| 关 键 词： | 5-羟色胺 肺动脉 脑室 迷走神经 纳络酮 |
The effect of 5-HT on the pulmonary arterial pressure of rabbits while injected of 5-HT into lateral ventricle of brain or vein |
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| Wu Bian-Ying,Li Chao-Ying,et al.The effect of 5-HT on the pulmonary arterial pressure of rabbits while injected of 5-HT into lateral ventricle of brain or vein[J].Chinese Journal of Pathophysiology,1992(6). |
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| Authors: | Wu Bian-Ying Li Chao-Ying |
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| Institution: | Wu Bian-Ying,Li Chao-Ying,et al Department of Pathophysiolog,Hebei Workers' Medical College,Baoding |
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| Abstract: | The change of Psa and Ppa was observed during injection of 5-HT into the lateral ventricle of brain or the auricular vein of anesthetized rabbits. Increase of Ppa and decrease of Psa were found after injection through auricular vein. On the contrary, while 5-HT was injected into lateral ventricule there were increased of Psa and decreased of Ppa. The responses of Ppa induced by 5-HT injecting into lateral ventricle might be related to the transmission of vagus and the action of Ach. The opiumnoid substances might take part in the change of Ppa and Psa while 5-HT was injected into lateral ventricle of brain. |
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| Keywords: | 5-HT Pulmonary artery Cerebral ventricles Vagus nerve Nalonone |
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