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辛伐他汀治疗颈动脉粥样硬化斑块的临床观察
引用本文:林港,司文明. 辛伐他汀治疗颈动脉粥样硬化斑块的临床观察[J]. 基层医学论坛, 2011, 15(20): 586-587
作者姓名:林港  司文明
作者单位:长治市高新技术开发区中心医院,山西,长治,046000
摘    要:目的研究辛伐他汀稳定或者消退颈动脉粥样硬化斑块的临床效果。方法将114例高血脂合并颈动脉粥样硬化斑块患者随机进行分组,试验组给予辛伐他汀,对照组采用饮食控制或者服用非他汀类药物。分别于治疗后6个月、12个月检测LDL-C、TC和TG等指标,并检测颈动脉硬化斑块的变化。结果治疗组和对照组6个月和12个月LDL-C、TC等指标明显低于治疗前水平,差异有显著性(P〈0.05),但只有治疗组患者颈动脉粥样硬化斑块厚度、面积与治疗前比较明显下降,差异有统计学意义(P〈0.05)。结论辛伐他汀具有很好的降血脂作用,其治疗颈动脉粥样硬化斑块疗效显著,长期服用可以获得良好的消除斑块效果。

关 键 词:辛伐他汀  颈动脉粥样硬化  降血脂  临床观察

Clinical effect observation of simvastatin on carotid atherosclerotic plaques
Lin Gang,Si Wenming. Clinical effect observation of simvastatin on carotid atherosclerotic plaques[J]. Public Medical Forum Magazine, 2011, 15(20): 586-587
Authors:Lin Gang  Si Wenming
Affiliation:Lin Gang,Si Wenming.High-Tech Development Zone,Central Hospital of Changzhi city,changzhi,shanxi 046000
Abstract:Objective To study the clinical effects of Simvastatin in stable or regression carotid atherosclerosis.Methods 114 cases of hyperlipemia with carotid atherosclerosis were randomized to group the experimental group received simvastatin,control group of non-diet control,or taking statins.After treatment,respectively 6 months,12 months test LDL,TC and TG were measured,and changes in carotid plaque.Results LDL-C,TC and other indicators level in treatment group and control group for 6 months and 12 months was si...
Keywords:Simvastatin Carotid artery atherosclerosis Lipid Clinical observation  
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