| 甲状腺功能亢进患者药物治疗后脂联素水平变化 |
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| 引用本文： | 鞠海兵,舒子正,王光琳,李丽风,宋洁,阮兆娟.甲状腺功能亢进患者药物治疗后脂联素水平变化[J].实用全科医学,2011,9(4):540-541. |
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| 作者姓名： | 鞠海兵 舒子正 王光琳 李丽风 宋洁 阮兆娟 |
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| 作者单位： | 成都军区昆明总医院内分泌科,云南省昆明市,650032 |
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| 摘 要： | 目的探讨甲状腺功能亢进患者经抗甲状腺药物治疗前后脂联素的变化及相关因素。方法97例甲状腺功能亢进患者经6个月抗甲状腺药物治疗后，观察甲状腺功能恢复正常的78例患者治疗前后空腹血糖、胰岛素、血脂、脂联素水平和体重指数；对治疗前后血清脂联素与BMI、甲状腺激素、血脂、胰岛素抵抗指数等变量进行相关分析。结果治疗6个月后FT3、FT4、TSH恢复正常，BMI升高．HOMA—IR下降，血清脂联素水平下降。治疗前，血清脂联素与BMI、HOMA—IR呈负相关，与FT4、F13呈正相关；治疗后，血清脂联素仍然与VT4、FT3呈正相关，与BMI呈负相关。控制BMI、性别、年龄等因素后的偏相关分析表明血清脂联素仍然与FT4呈正相关。结论甲亢患者血清脂联素升高，甲状腺功能正常后恢复正常，甲状腺激素水平影响脂联素水平。
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| 关 键 词： | 甲状腺功能亢进 药物治疗 脂联素 |
Changes of Serum Adiponectin in Patients with Hyperthyroidism before and after Antithyroid Drug Therapy |
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| JU Hai-bing,SHU Zi-zheng,WANG Guang-lin,et al..Changes of Serum Adiponectin in Patients with Hyperthyroidism before and after Antithyroid Drug Therapy[J].Applied Journal Of General Practice,2011,9(4):540-541. |
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| Authors: | JU Hai-bing SHU Zi-zheng WANG Guang-lin |
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| Institution: | JU Hai-bing,SHU Zi-zheng,WANG Guang-lin,et al.Department of Endocrinology,Kunming General Hospital of Chengdu Military Area Command,Kunming 650032,Yunnan,China |
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| Abstract: | Objective To investigate the changes of serum adiponectin and correlation factors in patients with hyperthyroidism before and after antithyroid drug therapy.Methods Ninety-seven patients with hyperthyroidism were treated with antithyroid drug,and seventy-eight patients achieving euthyroid status after 6 months of antithyroid drug therapy were recruited.FBG,insulin,FT3,FT4,TSH,TG,TC,BMI and serum adiponectin level were measured before and after 6 months treatment;correlation analysis between adiponectin and ... |
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| Keywords: | Hyperthyroidism Antithyroid drug therapy Adiponectin |
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