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中西医结合治疗酒依赖急性戒断期的半随机对照试验
引用本文:杜万君. 中西医结合治疗酒依赖急性戒断期的半随机对照试验[J]. 中国循证医学杂志, 2004, 4(8): 541-544
作者姓名:杜万君
作者单位:首都医科大学附属北京安定医院中国药物依赖治疗中心,北京,100088
摘    要:目的比较中西医结合治疗与单纯西医治疗酒依赖患者急性戒断期的疗效.方法将符合DSM-V酒依赖及急性酒戒断综合征标准的62例患者按人院顺序随机分成两组,奇数为观察组,共31例(4例因提前出院而排除),偶数为对照组,共31例.观察组根据中医四诊资料辨证分为四型.观察组予安定替代、凯西来、输液支持治疗及中药汤剂每日一剂;对照组除不服中药外其余治疗与观察组相同.结果观察组患者的肝功能恢复优于对照组,其中两组治疗前后GOT、γ-GT差值比较有统计学差异(P分别为0.046和0.001).焦虑抑郁量表测查减分,观察组均优于对照组,其中HAMD减分差异有统计学意义(t=3.165,P=0.003).平均安定治疗天数,观察组明显少于对照组(t=-2.666,P=0.01),安定平均使用总量,观察组亦少于对照组,但差异无统计学意义(P=0.434).结论酒依赖急性戒断期中西医结合治疗优于单纯西医治疗.

关 键 词:酒依赖  中西医结合治疗
文章编号:1672-2531(2004)08-0541-04
修稿时间:2004-06-22

Quasi-Randomized Controlled Trial of Integrated Traditional Chinese with Western Medicine for Acute Episodes of Withdrawal in Alcoholism
DU Wan-jun.National Drug Dependence Treatment Center,Beijing Anding Hospital Affiliated to Capital University of Medical Sciences,Beijing ,China. Quasi-Randomized Controlled Trial of Integrated Traditional Chinese with Western Medicine for Acute Episodes of Withdrawal in Alcoholism[J]. Chinese Journal of Evidence-based Medicine, 2004, 4(8): 541-544
Authors:DU Wan-jun.National Drug Dependence Treatment Center  Beijing Anding Hospital Affiliated to Capital University of Medical Sciences  Beijing   China
Affiliation:DU Wan-jun.National Drug Dependence Treatment Center,Beijing Anding Hospital Affiliated to Capital University of Medical Sciences,Beijing 100088,China
Abstract:
Keywords:Alcohol dependence  Integrated traditional Chinese with Western medicine
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