| 米氮平与曲唑酮、马普替林治疗抑郁症对照研究 |
| |
| 引用本文： | 姚晓伟. 米氮平与曲唑酮、马普替林治疗抑郁症对照研究[J]. 药物流行病学杂志, 2006, 15(4): 202-203 |
| |
| 作者姓名： | 姚晓伟 |
| |
| 作者单位： | 浙江省丽水学院医学部,浙江,丽水,323000 |
| |
| 摘 要： | 目的：评价米氮平与曲唑酮、马普替林治疗抑郁症的疗效及不良反应。方法：将符合《中国精神障碍分类与诊断标准》第3版诊断标准的抑郁症住院和门诊患者121例，随机平分为三组，分别给予米氮平和曲唑酮、马普替林治疗，疗程6周。用汉密尔顿抑郁量表（HAMD）、汉密尔顿焦虑量表（HAMA）、临床疗效总评量表的病情严重程度（CGI-S1）和不良反应量表（TESS），评定疗效和不良反应。结果：6周治疗后，3组总分均有显著下降，3组间疗效比较差异无统计学意义（P〉0、05）。结论：米氮平能更迅速的起效，对抑郁症的各个症状均有突出表现，是一种安全、有效的抗抑郁药。
|
| 关 键 词： | 米氮平 曲唑酮 马普替林 抑郁症 |
| 文章编号： | 1005-0698（2006）04-0202-02 |
| 收稿时间： | 2005-12-20 |
| 修稿时间： | 2005-12-20 |
Study of the Treatment of Depression with Mirtazapine, Trazodone and Maprotine |
| |
| Yao Xiaowei. Study of the Treatment of Depression with Mirtazapine, Trazodone and Maprotine[J]. Chinese Journal of Pharmacoepidemiology, 2006, 15(4): 202-203 |
| |
| Authors: | Yao Xiaowei |
| |
| Affiliation: | Medical board of Lishui College, Zhejiang 323000,P, R, China |
| |
| Abstract: | Objective: To compare the efficacy and side effects of remeron, trazodone and maprotine in the treatment of depression. Method: In this study, 121 patients with diagnostic depression according to CCMD-3 were randomly assigned to remeron group, trazodone group and maprotine group and the treatment lasted 6 weeks. Their effects and side reactions were evaluated by means of HAMD, HAMA, CCI-SI and TESS before and after the treatment. Result: Remeron produced quicker effects and its side effects were fewer than those of trazodone and maprotine. Conclusion: Remeron's rapid effect is prominent on all symptoms of depression. Remeron is an effective and safe antidepressant. |
| |
| Keywords: | Mirtazapine Trazodone Maprotine Depression |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
