| Involvement of medulary tail-flick related neurons in descending facilitation evoked by chemical stimulation of rat lateral habenular nucleus |
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| 引用本文： | 黄洛秀,程珍凤. Involvement of medulary tail-flick related neurons in descending facilitation evoked by chemical stimulation of rat lateral habenular nucleus[J]. Acta pharmacologica Sinica, 1998, 0(1) |
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| 作者姓名： | 黄洛秀 程珍凤 |
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| 作者单位： | 复旦大学生理学与生物物理学系立人实验室(黄洛秀)，西安医科大学生理学教研室(程珍凤) |
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| 摘 要： | 研究外侧缰核内微量注射Ｌ谷氨酸钠对大鼠延髓甩尾相关神经元活动和甩尾反射的影响．方法：用辐射热烫尾并同步记录延髓头端腹内侧区神经元单位放电和甩尾反射．结果：外侧缰核内微量注射Ｌ谷氨酸钠可加强给型甩尾相关细胞自发放电，抑制撤型甩尾相关细胞的自发放电，两类细胞的自发放电率分别从注射前的５８±２２Ｈｚ和１１．８±２２Ｈｚ变为注射后的１０９±３４Ｈｚ和６１±２２Ｈｚ．同时易化了两类细胞的甩尾相关反应和伤害剌激引起的甩尾反射，甩尾反射潜伏期从注射前的４０４±０１７ｓ缩短为注射后的２９７±０１３ｓ．结论：外侧缰核对节段性防御反射有下行易化作用，这种易化作用是通过延髓内撤型和给型甩尾相关细胞的协同活动而实现的．
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| 关 键 词： | 缰核；谷氨酸钠；延髓；神经元；电生理学；尾；痛测定 |
Involvement of medullary tail flick related neurons in descending facilitation evoked by chemical stimulation of rat lateral habenular nucleus |
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| HUANG Luo Xiu. Involvement of medullary tail flick related neurons in descending facilitation evoked by chemical stimulation of rat lateral habenular nucleus[J]. Acta pharmacologica Sinica, 1998, 0(1) |
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| Authors: | HUANG Luo Xiu |
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| Affiliation: | HUANG Luo Xiu 2 |
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| Abstract: | |
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| Keywords: | habenula sodium glutamate medulla oblongata neurons electrophysiology tail pain measurement |
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