| 法莫替丁与泮托拉唑预防重度颅脑损伤并发应激性消化道出血成本-效果分析 |
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| 引用本文： | 孟永康,王乐夫,武福南,丁志龙,王自华.法莫替丁与泮托拉唑预防重度颅脑损伤并发应激性消化道出血成本-效果分析[J].现代中西医结合杂志,2010,19(15):1833-1834,1851. |
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| 作者姓名： | 孟永康 王乐夫 武福南 丁志龙 王自华 |
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| 作者单位： | 湖南省攸县人民医院,湖南,攸县,412300 |
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| 摘 要： | 目的比较法莫替丁与泮托拉唑预防重度颅脑损伤并发应激性消化道出血的经济效果。方法将240例重度颅脑损伤的患者随机分成3组,法莫替丁组80例给予法莫替丁治疗5～40 d,泮托拉唑组80例给予泮拉唑治疗5～10 d,对照组未使用预防应激性溃疡的药物,对比其应激性溃疡的预防用药成本及发生率。结果法莫替丁组、泮托拉唑组与对照组的应激性溃疡的发生率分别为14%,9%和26%,3组比较有显著性差异(P均0.05);成本-效果比法莫替丁组为94.14,泮托拉唑组为1 104.66,2组比较有显著性差异(P0.05)。结论重度颅脑损伤后应用法莫替丁与泮托拉唑均能抑制胃酸,预防应激性溃疡,法莫替丁更为经济。
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| 关 键 词： | 重度颅脑损伤 上消化道出血 法莫替丁 泮托拉唑 成本-效果分析 |
Cost effectiveness analysis of famotidine and pantoprazole for prevention of severe craniocerebral injury complicated by upper gastrointestinal bleeding |
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| Meng Yongkang,Wang Lefu,Wu Funan,Ding Zhilong,Wang Zihua.Cost effectiveness analysis of famotidine and pantoprazole for prevention of severe craniocerebral injury complicated by upper gastrointestinal bleeding[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2010,19(15):1833-1834,1851. |
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| Authors: | Meng Yongkang Wang Lefu Wu Funan Ding Zhilong Wang Zihua |
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| Institution: | Meng Yongkang,Wang Lefu,Wu Funan,Ding Zhilong,Wang Zihua(The People\' Hospital of You County,You County 412300,Hunan,China) |
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| Abstract: | Objective It is to evaluate cost effectiveness analysis of famotidine and pantoprazole for the prevention of severe craniocerebral injury complicated by upper gastrointestinal bleeding.Methods 240 patients with severe craniocerebral injury were randomly divided into 3 groups with 80 cases each group.Famotidine group was treated by famotidine for 5 to 40 days;pantoprazole group was treated by pantoprazole for 5 to 10 days;control group was given nothing for prevention of stress ulcer.The cost and prevention ... |
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| Keywords: | severe craniocerebral injury upper gastrointestinal bleeding famotidine pantoprazole cost effectiveness analysis |
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