Magnetic Resonance (MR) Metabolic Imaging in Glioma |
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Authors: | Myriam M. Chaumeil Janine M. Lupo Sabrina M. Ronen |
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Affiliation: | 1. Department of Radiology and Biomedical ImagingMission Bay Campus;2. Brain Tumor Research Center, University of California, San Francisco, CA |
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Abstract: | This review is focused on describing the use of magnetic resonance (MR) spectroscopy for metabolic imaging of brain tumors. We will first review the MR metabolic imaging findings generated from preclinical models, focusing primarily on in vivo studies, and will then describe the use of metabolic imaging in the clinical setting. We will address relatively well‐established 1H MRS approaches, as well as 31P MRS, 13C MRS and emerging hyperpolarized 13C MRS methodologies, and will describe the use of metabolic imaging for understanding the basic biology of glioma as well as for improving the characterization and monitoring of brain tumors in the clinic. |
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Keywords: | brain tumors glioma magnetic resonance imaging metabolic imaging |
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