野生马齿苋抗动脉粥样硬化形成的实验研究

用野生马齿苋饲高脂膳食家兔作为实验性高脂血症和动脉粥样硬化（ＡＳ）的预防实验。通过血脂、血粘度及透射电镜下主动脉内膜超微结构的变化，探讨其作用机理。结果表明：１．野生马齿苋明显降低血清总胆固醇（ＴＣ），甘油三脂（ＴＧ）及低密度脂蛋白胆固醇（ＬＤＬ－Ｃ），升高血清高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）。２．野生马齿苋可降低全血低切表观粘度，可明显降低血浆中切表观粘度，对全血中切表观粘度也有降低趋势。３．电镜观察显示野生马齿苋能有效地减轻主动脉壁脂质沉积，并有抑制动脉粥样硬化斑块形成的作用。

THE EFFECT OF WILD PURSLANE ON ATHEROSCLEROSIS IN RABBITS

The effects of wild purslane on serum lipids,blood viscosity and atherosclerosis were investigated in rabbits.Each animal was given eight gram wild purslane/day for 11 weeks.The results showed:1.Purslane could markedly decrease serum TC、TG and LDL C concentration,but obviously increase HDL C concentration. There were significant differences compared to the positive control group.2.Purslane could effectively lower plasma middle shearing viscosity and whole blood low shearing viscosity,it also showed a tendency to lower the levels of whole blood middle shearing viscosity,but it did not reach a statistical significance.3.It was proved under the observation of electron microscope that purslane could lower lipids deposition of aorta intima and inhibit the formation of atherosclerotic plaque.