经支气管动脉介入治疗肺癌58例疗效分析

目的探讨支气管动脉化疗栓塞术治疗肺癌的临床疗效及应用价值。方法对58例肺癌患者行支气管动脉造影明确其分支及肿瘤血管情况,超选择性插管至肿瘤供血动脉,先行局部化疗药物(含顺铂、丝裂霉素及5-FU)灌注,后以碘化油加顺铂混合乳剂进行栓塞。结果58例大多血供丰富,二次介入治疗者肿瘤血管减少。完全缓解5例,部分缓解43例,稳定10例。有效率82.8%。症状总缓解率55.7%。结论支气管动脉化疗栓塞术治疗肺癌近期疗效较好,可以明显缓解症状,提高患者的生存质量。

Transbronchial arterial intervention treatment of lung cancer in 58 cases:An analysis of therapeutic effects

Objective To evaluate curative effect of transbronchial arterial intervention treatment of lung cancer. Methods The 58 patients were included in this study. First, bronchial arteriography was performed to identify the tumor-feeding branch, and to take super-selective catheterization into it. After cisplatin, mitomycin and 5-FU was infused,embolization with mixture of Lipodol and cisplatin was carried out.Results The tumor blush of 49 patients stained obviously. The feeding arteries of 28 patients through the second treatment decreased obviously. In the 58 patients, complete response were obtained in 5, partial response in 43, steady disease in 10, and no deterioration was seen. The overall response rate was 82.8%; relieved rate of clinical symptoms was 55.7%. Conclusion Transbronchial arterial intervention by super-selective tumor-feeding arteries catheterization has good short-term effect in the treatment of lung cancer and the clinical symptoms were relieved evidently.