氨溴特罗口服液佐治小儿肺炎支原体肺炎疗效分析

目的 观察氨溴特罗口服液协助治疗小儿肺炎支原体肺炎的临床疗效,探讨肺炎支原体肺炎发病机制.方法 将96例肺炎支原体肺炎住院患儿完全随机分为治疗组48例、对照组48例,2组患儿均采用阿奇霉素治疗,治疗组在此基础上联合氨溴特罗口服液,连续治疗7 d.观察2组临床总有效率和不良反应率并记录病情好转时间.结果 治疗组总有效率93.8%(45/48)明显好于对照组的85.4%(41/45)(x2=11.68,P＜0.05),住院期间治疗组患儿肺部哮鸣音消失时间、止咳时间、肺部啰音消失时间及住院时间均比对照组明显缩短分别为(2.3±1.1)d比(4.2±1.6)d,(3.4±1.1)d比(6.0±2.3)d,(3.3±1.2)d比(4.9±2.1)d,(5.8±1.0)d比(7.8±2.4)d].2组不良反应率较小,差异无统计学意义(P＞0.05).结论 氨溴特罗口服液联合阿奇霉素治疗小儿支原体肺炎疗效确切,安全,有助于缩短疗程.

Abstract：

Objective To study the effect of ambroxol hydrochloride and clenbuterol hydrochloride oral solution in treating mycoplasma pneumonia pneumonia, and to explore the possible immunopathogenesis. Methods Ninety-six hospitalized children with mycoplasma pneumonia were randomly divided in two groups. The treatment group (n=48) received ambroxol hydrochloride and clenbuterol hydrochloride oral solution in addition to conventional therapy and the control group (n=48) received routine therapy. Results The curative effect of the treatment group was superior to that of the control group93.8% vs 85.4%, P＜0.05]. The disappearance time of the lungs wheeze, cough time, pulmonary rales disappeared time and length of stay of children in the treatment group were significantly shorter than that in the control group (2.3 ±1. 1)d vs(4.2 ± 1. 6)d, (3.4 ± 1. 1)d vs(6. 0 ±2. 3)d, (3.3±1.2)d vs(4.9 ±2.1)d, (5.8±1.0)d vs(7.8±2.4)d]. Conclusion Oral administration of ambroxol hydrochloride and clenbuterol hydrochloride oral solution combined azithromycin is effective, secure and convenient for treatment of patients with mycoplasma pneumonia.

Analysis of ambroxol hydrochloride and clenbuterol hydrochloride oral solution in treating mycoplasma pneumonia

Objective To study the effect of ambroxol hydrochloride and clenbuterol hydrochloride oral solution in treating mycoplasma pneumonia pneumonia, and to explore the possible immunopathogenesis. Methods Ninety-six hospitalized children with mycoplasma pneumonia were randomly divided in two groups. The treatment group (n=48) received ambroxol hydrochloride and clenbuterol hydrochloride oral solution in addition to conventional therapy and the control group (n=48) received routine therapy. Results The curative effect of the treatment group was superior to that of the control group93.8% vs 85.4%, P＜0.05]. The disappearance time of the lungs wheeze, cough time, pulmonary rales disappeared time and length of stay of children in the treatment group were significantly shorter than that in the control group (2.3 ±1. 1)d vs(4.2 ± 1. 6)d, (3.4 ± 1. 1)d vs(6. 0 ±2. 3)d, (3.3±1.2)d vs(4.9 ±2.1)d, (5.8±1.0)d vs(7.8±2.4)d]. Conclusion Oral administration of ambroxol hydrochloride and clenbuterol hydrochloride oral solution combined azithromycin is effective, secure and convenient for treatment of patients with mycoplasma pneumonia.