经尿道等离子体前列腺切除联合抗雄治疗合并膀胱颈梗阻晚期高危前列腺癌

目的 探讨经尿道等离子体前列腺切除联合抗雄治疗合并膀胱颈梗阻晚期高危前列腺癌的临床意义.方法 采用经尿道前列腺等离子切除术、去势术以及间歇雄激素阻断等综合方法治疗合并膀胱出口梗阻的晚期高危前列腺癌患者14例.结果 所有手术均成功施行.术前及术后3个月复查尿动力学指标,患者最大尿流率由(8.0±3.2)ml/s上升为(1...

Transurethral resection of PKRP unity against androgen therapy prostate merger bladder neck obstruction high-risk prostate cancer late

Objectives Discussion PKRP joint androgen deprivation therapy high-risk merger bladder neck obstruction of the highly dangerous adanced prostate cancer clinical significance.Methods 14 cases of prostatic carcinoma complicated with bladder outlet obstruction were treated with bilateral orehidectomy combined with transurethral resection of the prostate plasma(PKRP)and intermittent nude hormone blockage.Results All the operations succeeded.Preoperative and postoperative 3 months review urine dynamics index,Qmax increased from (8.0±3.2)ml/s to(18.5±2.6)ml/s(p<0.05),IPSS decreased from(29.0±3.1)preoperatively to(8.0±1.5)postoperatively(p<0.05),QOL decreased from(4.4±1.3)to(2.3±0.5)(p0.05),,PSA decreased from (51.3±19.4)ng/ml to(8.8±6.1)ng/ml(P0.01).The follow up was 6months to today.2 cases died of prostatic carcinoma and 1 cases died of other diseases.The others survived with carcinoma.Conclusions Combined therapy,which includes bilateral orchidectomy,PKRP and intermittent male hormone blockage,for prostatic carcino ma complicated with bladder outlet obstruction has advantages of minimal trauma and rapid recovery.It can prolong life span,improve the quality of life,and be worth of wide application.