| 定量蛋白质组学在系统性红斑狼疮疾病中的应用 |
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| 引用本文： | 眭维国,汤冬娥,戴勇.定量蛋白质组学在系统性红斑狼疮疾病中的应用[J].国际免疫学杂志,2011,34(4):245-247,261. |
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| 作者姓名： | 眭维国 汤冬娥 戴勇 |
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| 作者单位： | 1. 中国人民解放军第181医院全军器官移植与透析治疗中心,广西代谢性疾病研究重点实验室,桂林,541002
2. 541002,桂林,中国人民解放军第181医院全军器官移植与透析治疗中心,广西代谢性疾病研究重点实验室;541004,桂林,广西师范大学生命科学学院 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 定量蛋白质组学的目的是对复杂的混合体系中所有的蛋白质进行鉴定,并对蛋白质量的变化进行测定,是当前生物科学研究中的重要内容.近年来,以质谱为基础的定量蛋白质组学技术在分析蛋白质组或亚蛋白质组方面取得令人瞩目的成就.对寻找和发现疾病中的特异标记物,对疾病的预防、诊断及疗效的监测方面具有重要作用.当前定量蛋白质组学在系统性红...
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| 关 键 词： | 定量蛋白质组学 系统性红斑狼疮 应用 |
Quantitative proteomics' Application in disease of systemic lupus erythematosus |
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| SUI Wei-guo,TANG Dong-e,DAI Yong.Quantitative proteomics' Application in disease of systemic lupus erythematosus[J].International Journal of Immunology,2011,34(4):245-247,261. |
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| Authors: | SUI Wei-guo TANG Dong-e DAI Yong |
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| Institution: | . PLA Transplantation and Hemopurification Center, 181 st Hospital of Guangzhou Military Area of PLA, Guangxi Key laboratory for Metabolic Diseases Research, Guilin 541002, China |
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| Abstract: | Quantitative proteomics is aimed to identify all the proteins in a complex mixed system, and to quantify the changes of the proteins In recent years, based on mass spectrometry ,made remarkable achievement was in analysis of proteins or sub-group proteins. These technologies play important roles in search for specific disease markers and for disease prevention, diagnosis and treatment. In this paper, we reviewed the current development and the application in systemic lupus erythematosus(SLE) of the quantitative proteomics. |
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| Keywords: | Quantitative proteomics Systemic lupus erythematosus Application |
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