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多体素1H磁共振频谱绝对定量脑内代谢物的方法
引用本文:霍珊珊,沈智威,陈耀文,黄璜,成小芳,吴仁华,邱庆春. 多体素1H磁共振频谱绝对定量脑内代谢物的方法[J]. 国际生物医学工程杂志, 2011, 34(3): 174-178. DOI: 10.3760/cma.j.issn.1673-4181.2011.03.011
作者姓名:霍珊珊  沈智威  陈耀文  黄璜  成小芳  吴仁华  邱庆春
作者单位:1. 汕头大学理学院物理系,515063
2. 汕头大学医学院,515041
3. 汕头大学工学院,515063
基金项目:国家自然科学基金重点项目,国家自然科学基金资助项目,广东省医学科研课题项目
摘    要:磁共振频谱(MRS)是一种利用磁共振原理和化学位移作用对一系列特定原子核及其化合物进行分析的方法.目前MRS的应用以1H谱最为广泛,其频谱技术已由单体素发展为三维多体素(3DCSI)扫描,为临床研究提供了许多重要的信息.就应用多体素磁共振频谱技术定量检测脑代谢物绝对浓度的方法进行综述.

关 键 词:磁共振频谱  多体素  绝对定量  脑代谢物

Review of absolute quantification of brain metabolites by using multi-voxel 1H-MRS
HUO Shan-shan,SHEN Zhi-wei,CHEN Yao-wen,HUANG Huang,CHENG Xiao-fang,WU Ren-hua,QIU Qing-chun. Review of absolute quantification of brain metabolites by using multi-voxel 1H-MRS[J]. International Journal of Biomedical Engineering, 2011, 34(3): 174-178. DOI: 10.3760/cma.j.issn.1673-4181.2011.03.011
Authors:HUO Shan-shan  SHEN Zhi-wei  CHEN Yao-wen  HUANG Huang  CHENG Xiao-fang  WU Ren-hua  QIU Qing-chun
Affiliation:. (Department of Physics Science College of Shantou University, Shantou 515063, China)
Abstract:The technology of Magnetic Resonance Spectroscopy(MRS) is a newly-developed mean for analyzing some specific nucleus and their compounds making use of the principles of magnetic resonance and the effects of chemical shift. Currently, among MRS applications, proton magnetic resonance spectroscopy (1HMRS) is the most widely applied one developed from single voxel to three-dimensional multi-voxel scanning technique. It provides a lot of important information for clinical studies. This article mainly reviews the methods for absolute quantification measurement of brain metabolites using multi-voxel MRS.
Keywords:Magnetic resonance spectroscopy  Multi-voxel  Absolute quantification  Brain metabolites
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