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卒中预防中的抗高血压药选择
引用本文:吴海侠,储照虎. 卒中预防中的抗高血压药选择[J]. 国际脑血管病杂志, 2011, 19(5): 389-392. DOI: 10.3760/cma.j.issn.1673-4165.2011.05.008
作者姓名:吴海侠  储照虎
作者单位:皖南医学院附属弋矶山医院神经内科,芜湖,241000
摘    要:控制高血压对于卒中预防至关重要.对于大多数患者来说,单药治疗往往不能使血压降至正常水平,而联合用药可提高降压效应,但并非所有降压药均效果良好.中国高血压干预效果研究的早期数据分析以及缬沙坦对血压未控制的心血管高危日本患者发病率和病死率影响研究的亚组分析显示,二氢吡啶类钙通道阻滞药氨氯地平和血管紧张素转换酶抑制药缬沙坦是...

关 键 词:卒中  抗高血压药  高血压  血管紧张素转换酶抑制药  钙通道阻滞药

Selection of antihypertensive drugs in stroke prevention
WU Hai-xia,CHU Zhao-hu. Selection of antihypertensive drugs in stroke prevention[J]. International Journal of Cerebrovascular Diseases, 2011, 19(5): 389-392. DOI: 10.3760/cma.j.issn.1673-4165.2011.05.008
Authors:WU Hai-xia  CHU Zhao-hu
Abstract:Control of hypertension is essential for stroke prevention. For most patients, the monotherapy often fails to lower blood pressure to normal levels, while the combination therapy can increase the effect of lowering blood pressure, however, not all the antihypertensive drugs have good efficacy. The early data analysis of the Chinese Hypertension Intervention Efficacy Study and the subgroup analysis of the KYOTO HEART study have showed that dihydropyridine calcium channel blocker amlodipine and angiotensin receptor blocker valsartan are both the most effective antihypertensive drugs in the prevention of stroke.
Keywords:Stroke  Antihypertensive agents  Hypertension  Angiotensin-converting enzyme inhibitors  Calcium channel blockers
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