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应用布地耐德雾化吸入治疗慢性阻塞性肺疾病急性加重期的临床观察
引用本文:孙建,周敏杰,封启明,赵钢. 应用布地耐德雾化吸入治疗慢性阻塞性肺疾病急性加重期的临床观察[J]. 国际呼吸杂志, 2011, 31(13): 977-979. DOI: 10.3760/cma.j.issn.1673-436X.2011.013.004
作者姓名:孙建  周敏杰  封启明  赵钢
作者单位:上海交通大学第六人民医院急诊科,200233
摘    要:目的 观察布地耐德(普米克令舒)雾化吸入对慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效.方法 92例AECOPD住院患者随机分为两组,观察组50例患者在常规治疗的基础上,给予吸入用布地奈德混悬液1 mg+氨溴索15 mg联合雾化吸入;对照组42例患者在常规治疗的基础上,甲强龙40 mg静脉滴注,氨溴索15 m...

关 键 词:布地耐德  雾化吸入  慢性阻塞性肺疾病急性加重期  糖皮质激素

Observation on pulmicort repuls inhalation of foggy in the treatment of chronic obstractive pulmonary disease at acute exacerbation phase
SUN Jian,ZHOU Min-jie,FENG Qi-ming,ZHAO Gang. Observation on pulmicort repuls inhalation of foggy in the treatment of chronic obstractive pulmonary disease at acute exacerbation phase[J]. International Journal of Respiration, 2011, 31(13): 977-979. DOI: 10.3760/cma.j.issn.1673-436X.2011.013.004
Authors:SUN Jian  ZHOU Min-jie  FENG Qi-ming  ZHAO Gang
Abstract:Objective To observe the clinic effect of pulmicort repuls inhalation acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods 92 patients with AECOPD were randomly divided into two groups:the observed group of 50 patients were given the treatment of budesonide (1 mg)inhalation of foggy twice a day, the control group of 42 patients were given the treatment of injection of methylprednisolone(40 mg)a day. Record the result of PaO2,PaCO2,pH,HCO3 on the seventh day,meanwhile observed the clinical symptoms as well as the side effect. Results The rate of efficiency of the observed group was 48. 00%. while the rate of the control group was 23. 81%, there was obvious difference between the two groups( P <0. 05). PaO2, PaCO2, pH, HCO3 of the patients of the two groups both improved. Conclusions The treatment of budesonide inhalation of foggy can improved the lung function and the clinical symptom of patients with AECOPD, which with a faster and better effect and less side-effect than glucocorticoid intravenously.
Keywords:Budesonide  Inhalation of foggy  Acute exacerbation of chronic obstructive pulmonary disease  Glucocorticoid
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