在急性心肌梗死合并心衰急诊治疗中新活素的应用价值探讨

目的：探讨在急性心肌梗死合并心衰急诊治疗中新活素的应用价值。方法：选取100例急性心肌梗死合并心力衰竭患者，随机分为观察组和对照组各50例，所有患者均给予常规基础治疗，观察组增加新活素静脉缓慢注射。对比观察2组患者的疗效、主要临床指标和不良反应情况。结果：观察组患者治疗总有效率为92％（46/50），明显高于对照组的74％（37/50），差异具有统计学意义（x2＝5．7406，P＜0．05）。观察组各项临床指标的改善均优于对照组，差异有统计学意义（P＜0．05）。2组间不良反应发生情况无明显差异（x2＝0．1221，P＞0．05）。结论：新活素用于急性心肌梗死合并心力衰竭的辅助治疗，可有效提高总有效率，改善各项临床指标，值得临床推广采用。

Application value investigation of Lrh-BNP in treatment of acute myocardial infarction combined heart failure

Objective：To explore application value of lyophilized recombinant human brain natriuretic peptide （ Lrh-BNP） in treat-ment of acute myocardial infarction combined heart failure .Methods：100 cases acute myocardial infarction combined heart failure were randomly divided into control group and treatment group , with 50 cases in each group .All patients were treated with routine treatment;treatment group were given Lrh -BNP additional by vein inject .Clinical curative effect , main clinical indicators and adverse reaction of the two groups were compared .Results：Clinical curative effect of treatment group （92%, 46/50） was obviously higher than that of control group （74%, 37/50）, the difference was significant （x2=5.7406,P〈0.05）;Main clinical indicators of treatment group were superior to control group （P〈0.05）.The adverse reaction was no significant difference （x2=0.1221,P〉0.05）.Conclusion：Lrh-BNP signifi-cantly improved the clinical curative effect and clinical indicators in adjuvant therapy of acute myocardial infarction combined heart failure with worth clinical promotion .