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In vivo acquisition of extended-spectrum beta-lactamase inSalmonella enteritidis during antimicrobial therapy |
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| Authors: | F Barguellil C Burucoa A Amor J L Fauchère C Fendri |
| Institution: | (1) Laboratoire de Microbiologie, Hopital militaire de Tunis, 1008 Montfleury, Tunis, Tunisia;(2) Laboratoire de Microbiologie A, Centre Hospitalier Universitaire La Miletrie, BP 577, 86021 Poitiers, France;(3) Laboratoire de Microbiologie, Centre Hospitalier Universitaire La Rabta, Tunis, Tunisia |
| Abstract: | The recovery of aSalmonella enteritidis strain that acquired resistance to  -lactams (including cefotaxime), to aminoglycosides and to chloramphenicol subsequent to cefotaxime therapy is reported. This resistance pattern to -lactams was due to the presence of an extended-spectrum -lactamase. The isoelectric point of this extended-spectrum -lactamase was 6.3. The resistance genes were located on a transferable high-molecular-weight plasmid. |
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