| S-腺苷甲硫氨酸的稳定性及其稳定性盐 |
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| 引用本文： | 申丽,李东阳,姜涌明,袁中一.S-腺苷甲硫氨酸的稳定性及其稳定性盐[J].药物生物技术,2003,10(2):125-128. |
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| 作者姓名： | 申丽 李东阳 姜涌明 袁中一 |
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| 作者单位： | 1. 扬州大学生物科学与技术学院,扬州,225009
2. 中国科学上海生命科学研究院生物化学和细胞生物学研究所,上海,200031 |
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| 摘 要： | S—腺苷甲硫氨酸是生物体内重要的中间代谢物质，参与多种生化反应，具有广泛和多样的治疗作用，但其内在的不稳定性在很大程度上限制了它在临床上的应用。文章主要介绍了S—腺苷甲硫氨酸的失活机理、稳定化理论及其新型稳定性盐。
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| 关 键 词： | S－腺苷甲硫氨酸 稳定性 稳定性盐 失活机理 |
| 文章编号： | 1005-8915(2003)02-0125-04 |
Stability and Stable Salts of S-adenosylmethionine |
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| SHEN Li ,LI Dong-yang ,JIANG Yong-ming ,YUAN Zhong-y i.Stability and Stable Salts of S-adenosylmethionine[J].Pharmaceutical Biotechnology,2003,10(2):125-128. |
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| Authors: | SHEN Li LI Dong-yang JIANG Yong-ming YUAN Zhong-y i |
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| Institution: | SHEN Li 2,LI Dong-yang 1,JIANG Yong-ming 2,YUAN Zhong-y i 1 |
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| Abstract: | S-adenosyl-L-methionine is an important m etabolic intermediate in org anism, which is involved in many biochemical reactions. Its therapeuctic usage c ould be extensive and varied, however its intrinsic instability limit its clini cal application to a large extent. This paper introduce its degradation mechanis m and stabilized theory, also refer to the novel stable salts of S-adenosyl -L-methionine with polyanions. |
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| Keywords: | S-adenosyl-L-methionine Degradation mech anism Stable salts of SAM with polyanions |
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