注射用复方氨苄西林钠药代动力学研究

目的:探讨威弛搽剂对急性软组织损伤的治疗作用。方法:用30只健康大耳白兔制作急性软组织损伤模型。将模型随机分为3组,每组10只,分别用威弛搽剂和红花油治疗,对照组治疗用生理盐水。观察各组急性软组织的肿胀、淤血及痛阈值情况,并进行组织形态学检查。结果:在消肿化淤和痛阈值等方面,威弛搽剂组明显好于红花油组及对照组;组织形态学显示威弛搽剂组炎性反应减轻快于红花油组和对照组。结论:威弛搽剂能抑制创伤性无菌性炎症反应,有良好的消肿散瘀作用,能明显减轻急性软组织损伤的疼痛,是治疗急性软组织损伤较为理想的药物。

Studies of the pharmacokinetics of compound ampicillin sodium for injection

Objective:To study the therapeutic effect of Weichi liniment on acute soft-tissue injury.Methods:Animal models of acute soft-tissue injury were made in 30 healthy white rabbits,and the animals were randomly divided into three groups(n=10 rabbits each):Weichi liniment,honghuayou and control group.The therapeutic effects were observed by methods of gross and histology.Re- sults:Weichi liniment bears better dispelling action of edema,analgesic action and dispelling stasis.The inflammation response of Weichi group to trauma in histology was significantly lighter compared with other 2 groups.Conclusion:Weichi liniment could inhibit traumatic aseptic inflammation and exert an effect of relieving swelling and dispersing blood stasis and might be an ideal external used drug in treating acute soft tissue injury.