基于有限元的单侧上颌骨缺损修复材料的生物力学研究

目的 采用三维有限元分析方法研究不同修复体材料对上颌骨单侧缺损修复的生物力学影响。方法 利用医学图像处理软件MIMICS重建单侧缺损上颌骨模型，采用镜像技术生成修复体模型，经模型处理最终建立单侧缺损修复的上颌骨有限元模型及健康上颌骨有限元模型，并模拟口腔咬合状态下上颌骨受力状态。结果 不同修复材料修复上颌骨的最大应力都集中在与颧骨连接的上颌骨边缘，即颧小肌与提口角肌附着位置。利用三磷酸钙（TCP）复合材料修复后，修复侧的上颌骨边缘应力最小为8.471 MPa；利用羟基磷灰石（HA）修复后，修复侧的上颌骨边缘应力最大，达到17.55 MPa。结论 不同修复材料对修复后上颌骨健侧受力影响不显著，对修复侧受力影响较大。弹性模量的大小可作为临床上用于缺损上颌骨修复的材料选择依据。

Biomechanical study on repair materials of unilateral maxilla defect based on finite element model

Objective To study the biomechanical effect from different prosthetic materials used on unilateral maxillary defect repair by three dimensional finite element (FE) analysis method. Methods The maxillary unilateral defect model was reconstructed by medical image processing software MIMICS. The prosthesis was generated by mirroring technology. After processing, the FE unilateral maxillary defect model and healthy maxillary model were established to simulate stress distributions on the maxilla during occlusion. Results The maximum stress on maxilla using different repair materials was always found concentrated on the edge of maxilla connected with zygoma (the positions attaching zygolabialis and levator anguli oris). The minimum stress of from the maxilla edge on the repair side was 8.471 MPa by using tricalcium phosphate (TCP) composite. The maximum stress from the maxilla edge on the repair side was 17.55 MPa by using hydroxyapatite (HA) material. Conclusions Different repair materials had no significant effect on natural side of the maxilla after restoration, while a greater impact of force status on the repair side was found. The elastic modulus of different repair materials can be used as a basis for maxilla restoration in clinic.