| ROS在火药烟雾致人支气管上皮细胞损伤中的作用 |
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| 引用本文： | 冯亮,乐家新,兰亚婷,庞伟,王成彬. ROS在火药烟雾致人支气管上皮细胞损伤中的作用[J]. 标记免疫分析与临床, 2010, 17(1): 27-29. DOI: 10.3969/j.issn.1006-1703.2010.01.011 |
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| 作者姓名： | 冯亮 乐家新 兰亚婷 庞伟 王成彬 |
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| 作者单位： | 解放军总医院临床检验科,北京,100853;解放军总医院临床检验科,北京,100853;解放军总医院临床检验科,北京,100853;解放军总医院临床检验科,北京,100853;解放军总医院临床检验科,北京,100853 |
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| 基金项目： | 全军医药卫生科研基金(06H045) |
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| 摘 要： | 研究活性氧（ROS）在火药烟雾致人支气管上皮细胞损伤中的作用。对支气管上皮细胞直接作用于火药烟雾环境中,观察不同时间火药对支气管上皮细胞活性影响及胞内ROS相对含量变化。结果表明培养的支气管上皮细胞的活性随着与火药烟雾接触时间的增加而降低,细胞内ROS相对含量随着时间的增加而升高。结论是细胞内ROS相对含量与细胞损伤程度相关,ROS是火药烟雾致支气管上皮细胞损伤机制重要部分。
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| 关 键 词： | 活性氧 火药烟雾 支气管上皮细胞 体外试验 |
The Role of ROS in Human Bronchial Epithelial Cell Injury Caused by Gunpowder Smoke |
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| FENG Liang,YUE Jia-xin,LAN Ya-ting,PANG Wei,WANG Cheng-bin. The Role of ROS in Human Bronchial Epithelial Cell Injury Caused by Gunpowder Smoke[J]. Labeled Immunoassays and Clinical Medicine, 2010, 17(1): 27-29. DOI: 10.3969/j.issn.1006-1703.2010.01.011 |
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| Authors: | FENG Liang YUE Jia-xin LAN Ya-ting PANG Wei WANG Cheng-bin |
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| Affiliation: | Department of Clinical Laboratory;Chinese PLA General Hospital;Beijing 100853;China |
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| Abstract: | To study the role of ROS in human bronchial epithelial cell injury caused by the smoke of gunpowder.The bronchial epithelial cells were directly treated on the gunpowder smoke-filled environment,the different processing time was used to observe live activity change and intracellular ROS levels of the bronchial epithelial cells.The results showed that the activity of bronchial epithelial cells decreased and ROS levels increased as time extended.The intracellular ROS levels associated with cell injury,ROS is ... |
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| Keywords: | ROS Gunpowder smoke Bronchial epithelial cells In vitro study |
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