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Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms
Authors:Turner Neil A  Aley Parvinder K  Hall Kersten T  Warburton Philip  Galloway Stacey  Midgley Lynne  O'Regan David J  Wood Ian C  Ball Stephen G  Porter Karen E
Affiliation:Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds LS2 9JT, UK.
Abstract:
Keywords:Statin   Tumor necrosis factor alpha   Cardiac fibroblast   Myofibroblast   MMP-9   Invasion   Migration   Rho kinase   Signal transduction pathways   siRNA
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