| 氯吡格雷在冠状动脉介入治疗中的临床观察 |
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| 引用本文： | 刘慧. 氯吡格雷在冠状动脉介入治疗中的临床观察[J]. 中国医药导报, 2010, 7(23) |
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| 作者姓名： | 刘慧 |
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| 作者单位： | 河南省南阳市中心医院心内科,河南南阳,473009 |
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| 摘 要： | 目的:探讨氯吡格雷在冠状动脉介入治疗中的有效性和安全性。方法:回顾性分析174例接受药物洗脱支架(DES)植入患者的临床资料。结果:氯吡格雷600、900mg组血小板聚集率(PA)抑制明显,发生氯吡格雷抵抗病例少,临床心血管事件发生少;主要出血事件各组之间无明显差别。结论:600、900mg组抑制PA效果更明显、临床心血管事件发生更少,600mg负荷剂量优势更明显。
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| 关 键 词： | 氯吡格雷 负荷剂量 冠状动脉介入术 药物涂层支架 |
Clinical observation of Clopidogreal in percutaneous coronary intervention |
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| LIU Hui. Clinical observation of Clopidogreal in percutaneous coronary intervention[J]. China Medical Herald, 2010, 7(23) |
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| Authors: | LIU Hui |
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| Affiliation: | LIU Hui (Department of Cardiology; Centre Hospital of Nanyang; He nan Province; Nanyang 473009; China); |
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| Abstract: | Objective:To investigate the efficacy and safety of Clopidogreal in percutaneous coronary intervention.Methods:The clinical data of 174 patients received drug-eluting stent (DES) implantation were retrospectively analyzed.Results:The time to the peak value of PA inhibition was lower in 600 mg and 900 mg groups than that in the other groups,the Clopidogrel resistance was also lower in 600 mg and 900 mg groups,the clinical cardiovascular event in 600,900 mg group was lower than the conventional loading dosage... |
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| Keywords: | Clopidogrel Loading dose Percutaneous coronary intervention Drug-eluting stent |
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