肝硬化顽固性腹水87例治疗分析

目的观察大量腹腔放液术（large volume paracentesis，LVP）联合白蛋白、右旋糖酐-40静脉滴注治疗肝硬化顽固性腹水的临床疗效。方法将肝硬化顽固性腹水87例，随机分成治疗组51例，对照组36例。治疗组采用LVP联合白蛋白、右旋糖酐-40静脉滴注治疗，对照组常规予利尿剂联合静脉滴注白蛋白治疗，统计治疗3周时的疗效及并发症发生率。结果治疗组腹水消退总有效率（96．1％）显著高于对照组（66．7％）（P〈O．05），治疗期间并发症发生率两组差异无显著性（P〉0．05）。结论LVP联合白蛋白、右旋糖酐-40静脉滴注治疗肝硬化顽固性腹水较传统疗法更加有效，且安全。

Refractory ascites cirrhosis treatment of 87 cases

Objective To investigate the clinical efficacy and complication rate of refractory ascites in liver cirrhosis by infusing albumin ,dextran 40 and releasing large volume paracentesis. Methods analysed 87 cases of refractory ascites in liver cirrhosis retrospectively and divided it into the treatment group 51cases and 36 cases of control group. The treat- ment group use LVP combined wish albumin, dextran 40, the control group use conventional diuretic theraph combined with intravenous infusion of albumin to statistic the efficacy and complications in three weeks. Results The totall effec- tive rate of ascites subsided in treatment group（96.1%） was significantly higher than control group（66.7%）（P〈0.05）. But the incidence of complications during treatment were no significant differences（P〉0. 05）. Conclusions The treat- ment of infusing albumin,dextran 40 in releasing LVP is more effective and safe than conventional therapy.