| 胎儿胃粘膜内分泌细胞免疫组化的定量研究 |
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| 引用本文： | 虞积耀,王鲁平,郑集义,雷道年. 胎儿胃粘膜内分泌细胞免疫组化的定量研究[J]. 解剖学杂志, 1995, 0(2) |
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| 作者姓名： | 虞积耀 王鲁平 郑集义 雷道年 |
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| 作者单位： | 海军总医院病理科!北京100037(虞积耀)，北京军区总医院(王鲁平，郑集义)，北京医科大学(雷道年) |
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| 摘 要： | 应用免疫组化方法对56例胎儿、5例新生儿、5例成人尸体解剖正常胃标本的内分泌细胞进行定量观察.第一抗体包括一嗜铬粒蛋白A、胃泌素、胃体抑素、五羟色胺、降钙素、绒毛膜促性腺激素、促肾上腺皮质激素、胰多肽、胰高血糖素、蛙皮素.应用图像分析系统对各类内分泌细胞进行定量测量.结果发现人胎儿胃内分泌细胞每平方厘米计数高于成人,尤其D细胞明显高于成人组(P<0.01).G细胞、D细胞、EC细胞、P细胞及CT阳性细胞分布与成人相似.在胎儿胃中还可见到成人胃中很少见到的绒毛膜促性腺激素、胰多肽、胰高血糖素阳性细胞.
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| 关 键 词： | 胎儿 胃 胃粘膜 内分泌细胞 |
A STUDY OF ENDOCRINE CELLS OF FETUS GASTRIC MUCOSA WITH IMMUNOHISTOCHEMICAL AND QUANTITATIVE METHODS |
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| Yu Jiyao,Wang Luping,Zheng Jiyi,Lei Daonian. A STUDY OF ENDOCRINE CELLS OF FETUS GASTRIC MUCOSA WITH IMMUNOHISTOCHEMICAL AND QUANTITATIVE METHODS[J]. Chinese Journal of Anatomy, 1995, 0(2) |
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| Authors: | Yu Jiyao Wang Luping Zheng Jiyi Lei Daonian |
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| Abstract: | The endocrine cells of gastric mucosa of 56 fetuses, 5 newborn and 5 adult cases were observed by immunohistochemical and quantitative methods. The first antibodies include antichromogranin A, gastrin, somatostatin, serotonin, glucagon, HCG, ACTH, pancreatic polypeptide, and bombesin calcitonin. The results indicated that endocrine cells, especially D cells, were higher than in adults in terms of mean per square millimetre. The distribution of endocrine cells in fetuses was similar to that in adults. HCG, pancreatic polypeptide and glucagon positive cells, which are very rare in adult gastric mucosa, were found in fetuses. |
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| Keywords: | fetus stomach gastric mucosa of fetus endocrine cell |
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