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Conformational changes of the N-terminal part of Mason-Pfizer monkey virus p12 protein during multimerization
Authors:Zdeněk Knejzlík  Martin Strohalm  Hana Lašt?vková  Michael Sakalian  Tomáš Ruml
Institution:a Department of Biochemistry and Microbiology, Institute of Chemical Technology, Technická 5, 166 28 Prague 6, Czech Republic
b Institute of Microbiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
c Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
Abstract:
Keywords:CA  capsid protein (domain)  CD  circular dichroism  CTD  C-terminal domain of capsid protein  CTRS  cytoplasmic targeting/retention signal  LILI  A-Np12  N-terminal part of the p12 protein (amino acid residues 1-41) with mutated residues L9  L16  I 13 and I20 to alanines  IP6  inositol hexakisphosphate  LZ  leucine zipper  LZ  A-Np12  N-terminal part of the p12 protein (amino acid residues 1-41) with mutated residues L22  L29 and L36 to alanines  MA  matrix protein (domain)  MMTV  mouse mammary tumor virus  M-PMV  Mason-Pfizer monkey virus  NC  nucleocapsid protein (domain)  NTD  N-terminal part of the capsid protein  PI(4  5)P2  phosphatidylinositol 4  5-bisphosphate  RSV  Rous sarcoma virus  VLP  virus-like particle  Wt-Np12  wild type N-terminal part of the p12 protein (amino acid residues 1-41)
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