氨溴索治疗社区获得性肺炎的安全性和有效性分析

目的分析氨溴索对社区获得性肺炎的治疗效果,并观察用药后的异常反应发生状况。方法选取2017年1月1日-2019年7月1日天津医科大学总医院滨海医院收治的社区获得性肺炎患者40例为研究对象,以信封法随机分为研究组和对照组,各20例。对照组给予常规治疗,而研究组在对照组基础上加用氨溴索治疗,比较两组临床疗效及异常反应发生率。结果研究组的总有效率为95.00%,明显高于对照组的65.00%,差异有统计学意义(P<0.05)。研究组异常反应发生率为10.00%,对照组的异常反应发生率为15.00%,差异无统计学意义(P>0.05)。结论氨溴索对社区获得性肺炎有良好的治疗效果,且没有增加患者的异常反应发生率,因此氨溴索治疗社区获得性肺炎具有较高的安全性和有效性。

The analysis of safety and efficacy of ambroxol in the treatment of community acquired pneumonia

Objective To analyze the therapeutic effect of ambroxol on community-acquired pneumonia and to observe the occurrence condition of abnormal reaction after administration. Methods From January 1,2017 to July 1,2019,forty patients with community-acquired pneumonia admitted to Binhai Hospital,Tianjin Medical University General Hospital were selected as the study objects and randomly divided into control group and study group with 20 cases in each group according to the envelope method. The control group was given routine treatment,while the study group was treated with ambroxol on the basis of the control group. The clinical efficacy and the incidence of abnormal reactions were compared between the groups. Results The total effective rate was 95.00% in the study group,which was higher than 65.00% in the control group,and the difference was statistically significant(P<0.05). The incidence of abnormal reaction in the study group was 10.00% and 15.00% in the control group,and the difference was not statistically significant(P>0.05). Conclusion Ambroxol had a good therapeutic effect on community-acquired pneumonia,and didn’t increase the incidence of abnormal reactions of patients. Therefore,ambroxol had the higher safety and efficacy in the treatment of community-acquired pneumonia.