狗牙根化学成分的研究

目的研究狗牙根的化学成分。方法狗牙根95%乙醇提取物正丁醇部位采用MCI、Rp-C18、半制备HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到13个化合物,分别鉴定为monocerin (1)、绿原酸甲酯(2)、4-O-香豆酰基奎宁酸甲酯(3)、5-O-阿魏酰奎宁酸(4)、异血红酸(5)、麦芽酚-β-D-吡喃葡萄糖苷(6)、1, 4-二甲氧基吩嗪(7)、19α-羟基齐墩果酮酸(8)、3-羟基-1-(4-羟基-3,5-二甲氧基苯基)-2-[4-(3-羟基-1-(E)-丙烯基)-2,6-二甲氧基苯氧基]丙基-β-D-吡喃葡萄糖苷(9)、4,5-二咖啡酰基奎宁酸甲酯(10)、苯甲酸(11)、4-羟基-邻茴香醛(12)、阿替匹林C(13)。结论所有化合物均为首次从该植物中分离得到。

Chemical constituents from Cynodon dactylon

AIM To study the chemical constituents from Cynodon dactylon(L.)Pars.METHODS The n-butanol fraction of 95% ethanol extract from C.dactylon was isolated and purified by MCI、Rp-C18and semi-preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Thirteen compounds were isolated and identified as monocerin(1), methyl chlorogenate(2), methyl-4-O-coumaroylquinate(3), 5-O-feruloylquinic acid(4), isohematinic acid(5), maltol-β-D-glucopyra noside(6), 1,4-dimethoxyphenazine(7), 19α-hydroxyoleanonic acid(8), 3-hydroxy-1-(4-hydroxy-3,5 dimethoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl)-2,6-dimethoxyphenoxy]propyl-β-D-gluco-pyranoside(9), 4,5-di-caffeo ylquinate(10), benzoic acid(11), 4-hydroxy-2-methoxy-benzaldehyde(12),artepillin C(13).CONCLUSION All the compounds are isolated from this plant for the first time.