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凤丫蕨化学成分研究
引用本文:陈佳佳,刘守金,高原,方成武. 凤丫蕨化学成分研究[J]. 安徽医药, 2010, 14(3): 277-279. DOI: 10.3969/j.issn.1009-6469.2010.03.010
作者姓名:陈佳佳  刘守金  高原  方成武
作者单位:安徽中医学院药学院,安徽省现代中药重点实验室,安徽,合肥,230031;云南西力生物技术有限公司,云南,昆明,650204
摘    要:目的研究风丫蕨Coniogramme japonica的化学成分。方法采用色谱法进行分离,根据理化性质和波谱数据鉴定化合物的结构。结果分离得到14个化合物,分别鉴定为onitisin(1)、1,3-双棕榈酸甘油酯(2)、5α,8α-过氧麦角甾-6,22E-二烯-3β-醇(3)、β-谷甾醇棕榈酸酯(4)、棕榈酸(5)、硬脂酸(6)、豆甾-4-烯-3β,6β-二醇(7)、芹菜素(8)、β-谷甾醇(9)、β-胡萝卜苷(10)、葡萄糖(11)、9S,12S,13S—trihydroxy-10-octadecenoic acid(12)、胡萝卜苷棕榈酸酯(13)、4-oxododecanedioic acid(14)。结论化合物1~3、5~8和11—14均是首次从凤丫蕨中得到。

关 键 词:凤丫蕨  化学成分  光谱分析

Chemical constituents of coniogramme japonica
CHEN Jia-jia,LIU Shou-jin,GAO Yuan,FANG Cheng-wu. Chemical constituents of coniogramme japonica[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(3): 277-279. DOI: 10.3969/j.issn.1009-6469.2010.03.010
Authors:CHEN Jia-jia  LIU Shou-jin  GAO Yuan  FANG Cheng-wu
Affiliation:1.Anhui Key Laboratory of Modernized Chinese Materia Medica;School of Pharmaceutical Sciences;Anhui College of TraditionalChinese Medicine;Hefei;Anhui 230031;China;2.BioBioPha Co.;Ltd.;Kunming;Yunnan 650204;China
Abstract:Aim To study the chemical constituents of Coniogramme japonica.Methods The Rhizome of C.japonica were extracted with ethanol and the chemical constituents were separated by chromatography technique,and their structures were determined by spectral analysis.Results Fourteen compounds were isolated and identified as onitisin(1),glycerol 1,3-dipalmitate(2),5α,8α-peroxy-ergosta-6,22E-diene-3β-ol(3),β-sitosterol palmitate(4),palmitic acid(5),stearic acid(6),stigmast-4-ene-3β,6β-diol(7),apigenin(8),β-sitosterol(9),β-daucosterol(10),glucose(11),9S,12S,13S-trihydroxy-10-octadecenoic acid(12),daucosterol palmitate(13)、4-oxododecanedioic acid(14).Conclusion Compounds 1 to 3,5 to 8 and 11 to 14 were isolated from Coniogramme japonica for the first time.
Keywords:Coniogramme japonica(Thunb.) Diels  chemical constituents  spectroscopic analysis
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