干体重达标对左心室心肌质量指数的影响

目的探讨干体重是否达标对左室心肌质量指数（LVMI）的影响及其与血压变化之间的关系。方法45例维持性血液透析患者随机分为超滤组（30例）和对照组（15例），于初始时及4周、8周时采集血压及超声心动图指标进行对比分析。结果初始时，对照组和超滤组的LVMl分别为136．3g／m2和138．7g/m2，2组差异有统计学意义（P〉0．05）。4周及8周时分别上升了3．5g/m2和0．4g／m2（P〉0．05）。而在超滤组，4周及8周时分别下降了7．5g／m2和6．3g／m2。比对照组4周时多下降11．0g／m2（P〈0．05），8周时多下降6．7g/m2（P〉0．05）。而初始时LVMI较高的患者中超滤组的血压下降更明显（P〈0．05）。结论干体重达标可降低善血透患者的LVMI，从而改善其预后。

Effect of probing dry-weight on left ventricular mass index

Objective To investigate the effect of probing dry-weight on left ventricular mass index （LV- MI） and to explore its relationship with blood pressure changes. Methods Forty-five patients who underwent maintenance hemodialysis were randomly divided into ultrafihration group （ n = 30） and control group （ n = 15 ）, the blood pressure in all the subjects was detected and echocardiogram indexes were analyzed at beginning,4 weeks and 8 weeks. Results At beginning, LVMI in control group and uhrafihration group was 136. 3g/m2 and 138.7g/m2 ,respectively,there was a significant difference between two groups （ P 〈0.05 ） ,which at 4 weeks and 8 weeks in control group was increased by 3.5g/m2 and 0.4g/m2, respectively （ P 〈 0.05 ）. However LVMI at 4 weeks and 8 weeks in uhrafihration group was decreased by 7.5g/m2 and 6.3g/m2, respectively, the decrease degree was 11.0g/m2 more than that in control group at 4 weeks （ P 〈 0.05 ） and 6.7 g/m2 at 8 weeks （ P 〈 O. 05）. Furthermore at beginning the blood pressure of patients with higher LVMI was more obviously decreased （P 〈 O. 05）. Conclusion The probing dry-weight up to the standard can decrease LVMI of patients undergoing hemodialysis, as a result, which can improve patient＇s prognosis.