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四物汤组方前后脂溶性化学成分的GC/MS分析
引用本文:周剑,李祥,武露凌.四物汤组方前后脂溶性化学成分的GC/MS分析[J].现代中药研究与实践,2008,22(3):35-38.
作者姓名:周剑  李祥  武露凌
作者单位:1. 南京中医药大学药学院,江苏,南京,210046;江苏省方剂重点实验室,江苏,南京,210046
2. 江苏省体育科学研究所,江苏,南京,210014
基金项目:江苏省方剂研究重点实验室开放课题 , 江苏省高校自然科学基金
摘    要:目的探讨四物汤及其组方中各单味药组方前后的脂溶性化学成分。方法采用索式提取法提取四物汤及其组方各单味药中的脂溶性成分,进行甲酯化处理后用气相色谱/质谱联用技术分离和鉴定其中成分的组成和含量。结果四物汤及其组方单味药熟地、白芍、当归和川芎中分别鉴定出25、38、41、30、51个化合物,分别占总量(不明确)的92.952%、76.093%、87.133%、70.304%、92.708%。结论四物汤及其组方各单味药主要成分均为不饱和脂肪酸类。

关 键 词:四物汤  当归  川芎  白芍  GC/MS

Analysis of the Liposoluble Constituent of Si-Wu Decoction Compound by GC/MS
ZHOU Jian,LI Xiang,WU Lu-Ling.Analysis of the Liposoluble Constituent of Si-Wu Decoction Compound by GC/MS[J].Research and Practice on Chinese Medicines,2008,22(3):35-38.
Authors:ZHOU Jian  LI Xiang  WU Lu-Ling
Institution:ZHOU Jian, LI Xiang, WU Lu-Ling( 1. College of Pharmacy, Nanjing University, Nanjing 210046, China; 2. Jiangsu Key Lab for TCM Formula Research ,Nanjing 210046 ,China; 3. Jiangsu Research Institute of Sports Science, Nanjing 210046, Chian)
Abstract:Objective To discuss the liposoluble constituent of Si-Wu decoction compound.Methods The liposoluble component from Si-Wu decoction and its combined compounds were extracted with petroleum ether by Soxlet extraction.The extracted liposoluble constituents were esterified and analyzed by GC/MS.Results Twenty-five,thirty-eight,forty-one, thirty and fifty-one compounds were identified in Si-Wu decoction and each single of rhizome rehmannia,paeoniae radix,angelica and chuanxiong,which accounted for over 92.952%,76.093%,87.133%,70.304% and 92.708% of total compounds,respectively.Conclusion Unsaturated fatty acids were the essential components of Si-Wu decoction and its combined compounds.
Keywords:Si-Wu decoction  the combined compounds of Si-Wu decoction  GC/MS
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