急性心肌梗死早期联合测定脑钠素与QT离散度的临床意义

目的探讨急性心肌梗死(AMI)早期联合测定脑钠素(BNP)与QT离散度对心脏恶性事件及梗死预后判断的临床价值。方法AMI患者急性期(发病后72h内)测定血浆BNP浓度及心电图QTd水平,并与对照组(CHD患者)进行对照;AMI患者中发生心脏恶性事件者与未发生者进行对照。结果AMI早期BNP浓度及QTd度均增加,与对照组相比差异显著(P<0.01),发生心脏恶性事件者其BNP与QT离散度增加更为显著,与未发生者相比差异显著(P<0.01)。结论BNP与QT离散度的联合测定对AMI早期心脏恶性事件的发生及梗死预后的判断具有较重要的临床价值。

Clinical Significance of Combined Detection of BNP and QT Diffusion in Early Stage of Acute Myocardial Infarction

Objective To discuss the clinical value of combined detection of BNP and QT diffusion in assessment of prognosis of AMI in early stage. Methods The plasma BNP, QTd and QTcd level of AMI in early stage were detected and compared with control group of CHD patient. The results of sudden cardiac attack of AMI were compared with those no attack patient. Results The BNP and QTd in early stage of AMI were increased with significant difference compared with control group (P<0.01). They were increased in sudden cardiac attack patient compared with those normal. Conclusion The combined detection of BNP and QTd might have important assessment value in clinic for the happening of sudden cardiac attack and prognosis of AMI in early stage.