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HIFU治疗超声衰减宽度<10 mm声通道腹壁瘢痕子宫肌瘤患者的有效性及安全性
引用本文:尹娜,王玲,胡亮,杨超,肖智博,陈锦云,王智彪. HIFU治疗超声衰减宽度<10 mm声通道腹壁瘢痕子宫肌瘤患者的有效性及安全性[J]. 中国介入影像与治疗学, 2018, 15(4): 221-225
作者姓名:尹娜  王玲  胡亮  杨超  肖智博  陈锦云  王智彪
作者单位:重庆医科大学生物医学工程学院省部共建国家重点实验室培育基地—重庆市超声医学工程重点实验室重庆市生物医学工程学重点实验室重庆市微无创医学协同创新中心;重庆医科大学附属第一医院超声消融治疗中心;重庆医科大学附属第一医院放射科;
基金项目:国家重大科研仪器设备研制专项(81127901)、国家自然科学基金面上项目(11574039)、重庆市教委科学技术研究项目(KJ1702039)。
摘    要:目的探讨超声引导下HIFU治疗声通道腹壁瘢痕造成超声衰减宽度10mm的子宫肌瘤患者的安全性及有效性。方法共纳入861例子宫肌瘤患者,于HIFU消融治疗前后行盆腔增强MR检查,其中202例腹壁瘢痕造成超声衰减宽度10mm(瘢痕组),659例无瘢痕(无瘢痕组),比较2组消融治疗效果、术中不良反应及术后并发症情况。结果对所有患者均完成HIFU治疗,瘢痕组和无瘢痕组子宫肌瘤体积消融率分别为(80.31±18.16)%、(79.60±17.57)%(P=0.620)。瘢痕组术中皮肤烫发生率[52.97%(107/202)]较无瘢痕组[41.58%(274/659)]高(P=0.004),瘢痕组和无瘢痕组术后MRI示腹壁水肿发生率分别为19.80%(40/202)、14.87%(98/659;P=0.095)。结论超声衰减宽度10mm的声通道腹壁瘢痕对HIFU治疗子宫肌瘤的有效性及安全性无明显影响。

关 键 词:平滑肌瘤  子宫  腹壁  瘢痕  高强度聚焦超声消融
收稿时间:2017-08-23
修稿时间:2018-01-29

Efficacy and safety of HIFU ablation for uterine fibroids in patients with abdominal surgical scars in acoustic pathway causing acoustic attenuation width <10 mm
YIN N,WANG Ling,HU Liang,YANG Chao,XIAO Zhibo,CHEN Jinyun and WANG Zhibiao. Efficacy and safety of HIFU ablation for uterine fibroids in patients with abdominal surgical scars in acoustic pathway causing acoustic attenuation width <10 mm[J]. Chinese Journal of Interventional Imaging and Therapy, 2018, 15(4): 221-225
Authors:YIN N  WANG Ling  HU Liang  YANG Chao  XIAO Zhibo  CHEN Jinyun  WANG Zhibiao
Affiliation:College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Biomedical Engineering, Chongqing Collaborative Innovation Center for Minimally-invasive and Noninvasive Medicine, Chongqing 400016, China,College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Biomedical Engineering, Chongqing Collaborative Innovation Center for Minimally-invasive and Noninvasive Medicine, Chongqing 400016, China,College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Biomedical Engineering, Chongqing Collaborative Innovation Center for Minimally-invasive and Noninvasive Medicine, Chongqing 400016, China,College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Biomedical Engineering, Chongqing Collaborative Innovation Center for Minimally-invasive and Noninvasive Medicine, Chongqing 400016, China;Ultrasound Ablation Center, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China,Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China,College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Biomedical Engineering, Chongqing Collaborative Innovation Center for Minimally-invasive and Noninvasive Medicine, Chongqing 400016, China;Ultrasound Ablation Center, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China and College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Biomedical Engineering, Chongqing Collaborative Innovation Center for Minimally-invasive and Noninvasive Medicine, Chongqing 400016, China
Abstract:
Keywords:Leiomyoma  Uterus  Abdominal wall  Cicatrix  High-intensity focused ultrasound ablation
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