Brain MRI in obsessive-compulsive disorder |
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| Authors: | C H Kellner R R Jolley R C Holgate L Austin R B Lydiard M Laraia J C Ballenger |
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| Affiliation: | Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425. |
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| Abstract: | Magnetic resonance imaging (MRI) brain scans were performed on 12 patients with obsessive-compulsive disorder and 12 healthy controls. Measurements of the area of the head of the caudate nucleus, cingulate gyrus thickness, intracaudate/frontal horn ratio, and area of the corpus callosum did not differ between the two groups. These limited data do not support the presence of a consistent gross brain structural abnormality in obsessive-compulsive disorder. Further studies using other anatomic measurements and other brain structural imaging techniques are warranted. |
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