| 丙型肝炎病毒感染者自身抗体的检测及其临床意义 |
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| 引用本文： | 柳永和,金燕,周韵九.丙型肝炎病毒感染者自身抗体的检测及其临床意义[J].中南大学学报(医学版),1996(4). |
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| 作者姓名： | 柳永和 金燕 周韵九 |
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| 作者单位： | Clinical laboratory，Xiangya Hospital，hunan Medical University |
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| 摘 要： | 检测３５例抗－ＨＣＶ阳性者的自身抗体情况，并与３０例ＨＢｓＡｇ阳性者及３２例正常人作对照。结果发现，ＨＣＶ阳性者ＥＮＡ阳性率为４２．９％，自身抗体总检出率为６２．９％，均明显高于正常对照组及ＨＢｓＡｇ阳性者（Ｐ＜０．０５）。提示抗－ＨＣＶ及ＨＢｓＡｇ阳性者可检出某种自身抗体，表明其免疫系统已受到不同程度的损害，应及时采取防治措施。讨论了丙型肝炎与自身免疫性肝炎的关系。
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| 关 键 词： | 丙型肝炎病毒 丙型肝炎 自身免疫性疾病 肝炎 自身抗体 抗体类，抗核 类风湿因子 |
DETECTION OF AUTO-ANITBODIES IN HCV CARRIERS AND THEIR CLINICAL SKGNIFICANCE |
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| Liu Yonghe,Jin Yan,Zhou Yungjiu.DETECTION OF AUTO-ANITBODIES IN HCV CARRIERS AND THEIR CLINICAL SKGNIFICANCE[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1996(4). |
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| Authors: | Liu Yonghe Jin Yan Zhou Yungjiu |
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| Abstract: | xtractable nuclear antibody(ENA),anti-nuclear antibody(ANA)and rheumatoid factor(RF)were determined in 35 cases of anti-hepatitis C virus(anti-HCV)carriers,30 cases of HB-sAg carriers and 32 cases of control.The total positive rate of auto-antibodies(62.9%)and thepositive rate of ENA(42.9%)in group of anti-HCV carriers were higher than those in group ofHBsAg carriers(33.3%and 16.7%)and in control group(6.2%and 3.1%)(P<0.05,P<0.01).The results indicate,when some auto-antibodies are determined in the anti-HCV andHBsAg carriers,their immune system is being injured.The relationship between hepatitis C andautoimmune hepatitis are discussed. |
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| Keywords: | hepatitis C virus hepatits C autoimmune disease hepatitis autoanti-body antibodies anti-nuclear rheumatoid factor |
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