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Design,Synthesis, and Anti‐HIV Evaluation of Novel Triazine Derivatives Targeting the Entrance Channel of the NNRTI Binding Pocket
Authors:Xuwang Chen  Qing Meng  Liyun Qiu  Peng Zhan  Huiqing Liu  Erik De Clercq  Christophe Pannecouque  Xinyong Liu
Institution:1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Ji'nan, Shandong, China;2. Department of Pharmacy, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong, China;3. Institute of Pharmacology, School of Medicine, Shandong University, Ji'nan, Shandong, China;4. Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
Abstract:
Keywords:antiviral activity  entrance channel  HIV‐1  molecular modeling  NNRTIs
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