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Normal outcome of pregnancy in chronic myeloid leukemia treated with interferon-alpha in 1st trimester: report of 3 cases and review of the literature
Authors:Mubarak A A S  Kakil I R  Awidi A  Al-Homsi U  Fawzi Z  Kelta M  Al-Hassan A
Affiliation:Hamad Medical Corporation, Department of Medicine, Hematology/Oncology Division, Doha, Qatar.
Abstract:Three patients with chronic myeloid leukemia (CML) in chronic phase received interferon-alpha during pregnancy, starting from the 1st trimester. No maternal complications were reported. The 3 patients delivered normal looking babies apart from one baby who was found to have transient mild thrombocytopenia. Subsequently these children were followed for 30, 12, and 4 months and all had normal growth and development.
Keywords:interferon‐α  chronic myeloid leukemia  essential thrombocythaemia  pregnancy
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