| 非痴呆老年人认知功能的差异性:从成功老化到轻度认知损伤 |
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| 作者姓名： | Wang W Xie H Wan Q Wang L |
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| 作者单位： | 1. 100853,北京,解放军总医院南楼神经内科
2. 第四军医大学西京医院神经内科 |
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| 基金项目： | 军队“十五”重点课题基金资助项目 (0 1Z0 3 7) |
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| 摘 要： | 目的：对非痴呆的自诉记忆力减退的老年人,就其总体认知水平而言可能存在相对同源的不同亚型进行初步探讨。方法：对34例调查者进行临床记忆量表等17种神经心理测验,将结果进行Q型聚类分析。结果：15例调查者被诊断为轻度认知损伤,占44％;聚类分析产生6类新样本。结论：在正常老化与早期阿尔茨海默病这一过渡期内,老年人的认知状态是不均质的,其中既有成功老化,也有一般老化,尤其是还存在着具有痴呆发病危险性的认知损伤。
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| 关 键 词： | 认知障碍 神经心理学测验 阿尔茨海默病 |
| 修稿时间： | 2002年2月28日 |
The cognitive variations among non-dementia elders: from successful aging to mild cognitive impairment |
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| Wang W,Xie H,Wan Q,Wang L.The cognitive variations among non-dementia elders: from successful aging to mild cognitive impairment[J].Chinese Journal of Internal Medicine,2002,41(10):671-674. |
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| Authors: | Wang Wei Xie Hengge Wan Qi Wang Luning |
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| Institution: | Department of Neurology, South Building, Chinese PLA General Hospital, Beijng 100853, China. wangwei301@hotmail.com |
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| Abstract: | OBJECTIVE: To study the heterogeneity of cognitive function in the non-demented elderly population with complaint of memory decline. METHODS: Neuropsychological tests were carried out in 34 subjects by using clinical memory scales including 17 variables and Q-type cluster analysis was performed. RESULTS: Fifteen subjects (44%) were diagnosed as mild cognitive impairment (MCI). Six new clusters were produced by cluster analysis. CONCLUSION: In the transitional period from normal aging to early Alzheimer's disease, the cognitive function of elders are heterogeneous, there may be cognition of successful aging, cognition of normal aging and even cognitive impairment with potential risk of dementia. |
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| Keywords: | Cognition disorders Neuropsychological test Alzheimer disease |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
